1. bookVolume 37 (2021): Issue 4 (December 2021)
Journal Details
Format
Journal
eISSN
1930-3955
First Published
01 Sep 1984
Publication timeframe
4 times per year
Languages
English
access type Requires Authentication

Prevalence of major blood group antigens in blood donors at a main donation center in United Arab Emirates

Published Online: 29 Dec 2021
Volume & Issue: Volume 37 (2021) - Issue 4 (December 2021)
Page range: 171 - 177
Journal Details
Format
Journal
eISSN
1930-3955
First Published
01 Sep 1984
Publication timeframe
4 times per year
Languages
English
Abstract

Blood transfusion is a common practice in hospitals. In many diseases, transfusion of red blood cells can be a life-saving measure. Knowing the blood group phenotypes of the donors in any population is important to improve health care services and to better serve patients. We aimed to determine the blood group phenotypes of the regular donors visiting the main blood donation center in Sharjah, United Arab Emirates (UAE). A total of 500 regular blood donors were included, and blood group antigens were tested using serologic methods. Major blood group systems included in this testing were ABO, Rh, Kell, Kidd, Duffy, Lewis, Lutheran, MNS, and P1PK. The most prevalent ABO/D blood type was group O, D+ (29.6%), with the most prevalent phenotype in the Rh blood group system reported as R1r (34.4%). In the Kell system, the K–k+ phenotype was reported in 92.4 percent of individuals tested. The rare Duffy null phenotype, Fy(a–b–), was reported in 11.0 percent of the cohort. Most donors (99.0%) were Lu(b+). In the Lewis system, the phenotype Le(a–b+) was seen in 61.8 percent of the donors. MNS system phenotypes were comparable to the reports from Saudi Arabia and India, with M+N+S–s+ being the most prevalent (21.2%). The prevalence of many major blood group phenotypes in the UAE blood donor population showed similarities to results from populations in neighboring countries, but other phenotype prevalences were unique to this population. This finding can be used to build a blood group registry for the local population that can better serve hospitals’ transfusion requirements.

Key Words

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