1. bookVolume 19 (2019): Issue 1 (April 2019)
Journal Details
License
Format
Journal
eISSN
1338-4139
First Published
03 Jun 2011
Publication timeframe
3 times per year
Languages
English
access type Open Access

Pupillary Light Reflex in Children with ADHD

Published Online: 09 May 2019
Volume & Issue: Volume 19 (2019) - Issue 1 (April 2019)
Page range: 30 - 37
Received: 19 Dec 2018
Accepted: 01 Mar 2019
Journal Details
License
Format
Journal
eISSN
1338-4139
First Published
03 Jun 2011
Publication timeframe
3 times per year
Languages
English
Abstract

Attention deficit/hyperactivity disorder (ADHD) is one of the most frequently seen mental disorders in children with an increasing risk for other mental disorders. ADHD represents a primary biological dysfunction of the central nervous system, such as dysregulation of frontal-subcortical-cerebellar catecholaminergic circuits and imbalances in the dopaminergic system. However, autonomic nervous system, comprised of two primary branches - sympathetic and parasympathetic nervous systems that are normally in dynamic balance, plays an essential role in the regulation of body functions. Although it is generally assumed that the autonomic regulation is impaired during ADHD the information related to this dysregulation is limited. One of the options to observe changes of autonomic balance in ADHD is pupillary light reflex (PLR). Pupillometric evaluation can be used for the assessment of functioning of both autonomic nervous system branches and certain parameters of pupil responsivity can be helpful as a tool for medical diagnostic and treatment. In conclusion, these findings suggest the pupillometry as a non-invasive method that can indicate abnormalities in the complex central autonomic network regulating PLR.

Keywords

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