1. bookVolume 71 (2021): Issue 3 (September 2021)
Journal Details
License
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Journal
First Published
25 Mar 2014
Publication timeframe
4 times per year
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English
access type Open Access

Fatal Disseminated Pseudomonas Aeruginosa Infection in a Captive Green Iguana (Iguana iguana)

Published Online: 27 Sep 2021
Page range: 361 - 370
Accepted: 27 Aug 2021
Journal Details
License
Format
Journal
First Published
25 Mar 2014
Publication timeframe
4 times per year
Languages
English
Abstract

Infections with various bacteria, especially gram-negative aerobes, are a well-recognized problem in captive cold-blooded animals with immunocompromised health status, or in those kept under poor conditions. Pseudomonas is one of the most represented genera. Here, we present a case of fatal disseminated infection caused by Pseudomonas aeruginosa in a captive green iguana kept at the “Pionirska dolina” Zoo in Sarajevo, Bosnia and Herzegovina. At necropsy, severe stomatitis, pneumonia, hepatitis and nephritis, accompanied with focally extensive dermatitis were observed. Histopathology revealed multifocal necrosis in various visceral organs. Culture and subsequent MALDI-TOF MS analysis were conducted to identify the isolate as P. aeruginosa. Antimicrobial susceptibility testing revealed a wide susceptibility of the isolate, however applied therapy was instilled too late in the presented case. This case demonstrates the significance of timely and accurate identification, and antimicrobial susceptibility testing of bacterial isolates implicated in the pathology of captive reptiles. The importance of monitoring the adequate environmental conditions (enclosure temperature, humidity and conformation), health status and possible clinical signs of illness are highlighted.

Keywords

1. Ebani VV, Fratini F, Ampola M, Rizzo E, Cerri D, Andreani E: Pseudomonas and Aeromonas isolates from domestic reptiles and study of their antimicrobial in vitro sensitivity. Vet Res Commun 2008, 32(Suppl 1):S195-S198. Search in Google Scholar

2. Schumacher J: Selected Infectious Diseases of Wild Reptiles and Amphibians. J Exot Pet Med 2006, 15(1):18-24. Search in Google Scholar

3. Romero SB, Čížek A, Masaříková M, Knote Z: Choanal and cloacal aerobicbacterial flora in captive green iguanas: a comparative analysis. Acta Vet Brno 2015, 84:19-24. Search in Google Scholar

4. Pasmans F. Martel A., Jacobson ER: Bacterial Diseases in reptiles. In: Jacobson E.R., Garner MM (Editors). Infectious Diseases and Pathology of Reptiles: Color Atlas and Text. 2nd ed. St. Louis, Missouri, USA: Elsevier/Saunders. 2021, 705-747. Search in Google Scholar

5. Johnson-Delaney CA: Reptile zoonoses and threats to public health. In: Mader DR (Editor). Reptile Medicine and Surgery. WB Saunders. 2006, 1017-1030. Search in Google Scholar

6. Jacobson ER: Reptiles. Vet Clin North Am: Exot Anim Pract 1987, 17(5):1203-1225. Search in Google Scholar

7. Foti M, Giacopello C, Fisichella V, Latella G: Multidrug-resistant Pseudomonas aeruginosa isolates from captive reptiles. J Exot Pet Med 2013, 22:270-274. Search in Google Scholar

8. Brockmann M, Aupperle-Lellbach H, Müller E, Heusinger A, Pees M, Marschang RE: Aerobic bacteria from skin lesions in reptiles and their antimicrobial susceptibility. Tierarztl Prax Ausg K Kleintiere Heimtiere 2020, 48:78-88. Search in Google Scholar

9. Chaprazov T, Dimitrov R, Stamova Yovcheva K: Oral abscess associated with cranial tooth loss in green iguana (Iguana iguana). Turk J Vet Anim Sci 2013, 37:615-617. Search in Google Scholar

10. Seixas R, Pissarra H, Santos JP, Bernardino R, Fernandes T, Correia J, Vilela CL, Oliveira M: Severe fibrinonecrotic enteritis caused by Pseudomonas aeruginosa in a captive monitor lizard (Varanus nuloticus). J Zoo Wildl Med 2014, 45(2):410-412. Search in Google Scholar

11. White SD, Bourdeau P, Bruet V, Kass PH, Tell L, Hawkins MG: Reptiles with dermatological lesions: a retrospective study of 301 cases at two university veterinary teaching hospitals (1992–2008). Vet Dermatol 2011, 22:150-161. Search in Google Scholar

12. Hilf M, Wagner RA, Yu VL: A Prospective Study of Upper Airway Flora in Healthy Boid Snakes and Snakes with Pneumonia. J Zoo Wildl Med 1990, 21(3):318-325. Search in Google Scholar

13. Schmidt V, Marschang RE, Abbas MD, Ball I, Szabo I, Helmuth R, Plenz B, Spergser J, Pees M: Detection of pathogens in Boidae and Pythonidae with and without respiratory disease. Vet Rec 2013, 172(9):236. Search in Google Scholar

14. Plenz B, Schmidt V, Grosse-Herrenthey A, Krüger M, Pees M: Characterisation of the aerobic bacterial flora of boid snakes: application of MALDI-TOF mass spectrometry. Vet Rec 2015, 176(11):285. Search in Google Scholar

15. Mader DR: Thermal burns. In: Mader DR (Editor). Reptile Medicine and Surgery. 2nd ed. St. Louis, USA: Saunders/Elsevier Inc. 2006, 916-923. Search in Google Scholar

16. Pees M, Hellebuyck T: Thermal Burns. In: Divers SJ, Stahl SJ (Editors). Mader,s Reptile and Amphibian Medicine and Surgery. 3rd ed. St. Louis, Missouri, USA: Saunders Elsevier. 2019, 1351-1352. Search in Google Scholar

17. Miller CL: Trauma and Physical Diseases. In: Garner MM, Jacobson ER (Editors). Noninfectious Diseases and Pathology of Reptiles: Color Atlas and Text. 1st ed. St. Louis, Missouri, USA: Elsevier/Saunders. 2021, 231-243. Search in Google Scholar

18. Khosravi AR, Shokri H, Rostami A, Tamai IA, Erfanmanesh A, Memarian I: Severe dermatophytosis due to Trichophyton mentagrophytes var. interdigitale in flocks of green iguanas (Iguana iguana). J Small Anim Pract 2012, 53, 286–291. Search in Google Scholar

19. Chung T-H, Kim E-J, Choi US: Multiorgan Fungal Infection Caused by Microsporum canis in a Green Iguana (Iguana iguana). J Zoo Wildl Med 2014, 45(2):393-396. Search in Google Scholar

20. Schumacher J: Reptile Respiratory Medicine. Vet Clin North Am: Exot Anim Pract 2003, 6:213-231. Search in Google Scholar

21. EUCAST, European Committee on Antimicrobial Susceptibility Testing. Intrinsic resistance and unusual phenotypes version 3.2, February 2020 (http://www.eucast.org/expert_rules_and_intrinsic_resistance/). Search in Google Scholar

22. Tang PK, Divers SJ, Sanchez S: Antimicrobial susceptibility patterns for aerobic bacteria isolated from reptilian samples submitted to a veterinary diagnostic laboratory: 129 cases (2005–2016). J Am Vet Med Assoc 2020, 257:305–312. Search in Google Scholar

23. Perry S, Mitchell M: Antibiotic therapy. In: Divers SJ, Stahl S, eds. Mader’s reptile and amphibian medicine and surgery. 3rd ed. St. Louis, Missouri, USA: Saunders Elsevier. 2019, 1139–1154. Search in Google Scholar

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