1. bookVolume 84 (2022): Issue 4 (January 2022)
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Journal
eISSN
2083-4594
First Published
24 Jan 2008
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4 times per year
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English
access type Open Access

Human mitochondrial DNA diversity is compatible with the multiregional continuity theory of the origin of Homo sapiens

Published Online: 01 Jan 2022
Page range: 487 - 502
Received: 12 May 2021
Accepted: 29 Nov 2021
Journal Details
License
Format
Journal
eISSN
2083-4594
First Published
24 Jan 2008
Publication timeframe
4 times per year
Languages
English
Abstract

Confidence intervals for estimates of human mtDNA sequence diversity, chimpanzee-human mtDNA sequence divergence, and the time of splitting of the pongid-hominid lineages are presented. Consistent with all the data used in estimating the coalescence time for human mitochondrial lineages to a common ancestral mitochondrion is a range of dates from less than 79,000 years ago to more than 1,139,000 years ago. Consequently, the hypothesis that a migration of modern humans (Homo sapiens) out of Africa in the range of 140,000 to 280,000 years ago resulted in the complete replacement, without genetic interchange, of earlier Eurasian hominid populations (Homo erectus) is but one of several possible interpretations of the mtDNA data. The data are also compatible with the hypothesis, suggested earlier and supported by fossil evidence, of a single, more ancient expansion of the range of Homo erectus from Africa, followed by a gradual transition to Homo sapiens in Europe, Asia, and Africa.

Keywords

Avise JC, Arnold J, Ball RM, Bermingham E, Lamb T, Neigel JE, Reeb CA, Saunders NC. 1987. Intraspecific phylogeography: the mitochondrial DNA bridge between population genetics and systematics. Ann Rev Ecol Syst 18(1):489–522.10.1146/annurev.es.18.110187.002421Search in Google Scholar

Avise, JC, Neigel JE, Arnold J. 1984. Demographic influences on mitochondrial DNA lineage survivorship in animal populations. J Mol Evol 20(1984):99–105.10.1007/BF022573696433037Search in Google Scholar

Barry JC. 1986. A review of the chronology of Siwalik hominoids. In: Else JG, Lee PC, editors. Primate Evolution. London: Cambridge University Press. 93–103Search in Google Scholar

Bednarik RG. 2015. The First Mariners. Bentham Science Publishers.Search in Google Scholar

Bernor RL. 1983. Geochronology and zoogeographic relationship of Miocene hominidea. In: RL Ciochon, RS Corrucini, editors. New Interpretations of Ape and Human Ancestry. New York: Plenum Press New York, 21–64.Search in Google Scholar

Cann RL, Stoneking M, Wilson AC. 1987. Mitochondrial DNA and human evolution. Nature 325(6099):31–6.10.1038/325031a03025745Search in Google Scholar

Dart RA. 1925. Australopithecus africanus The Man-Ape of South Africa. Nature 115:195–9.10.1038/115195a0Search in Google Scholar

Darwin C. 1896. The Descent of Man and Selection in Relation to Sex. New York: Appleton.Search in Google Scholar

Eckhardt RB. 1971. Hominoid Dental Variation and Hominid Origins. PhD diss. University of Michigan.Search in Google Scholar

Eckhardt RB, Eckhardt DA, Eckhardt JT. 1988. Are racehorses becoming faster? Nature 335(6193):773.10.1038/335773a03185707Search in Google Scholar

Eckhardt RB, Henneberg M. 2021. Paleospecies as cognitive construct: The meme of “Homo floresiensis.” Anthropol Rev 84(3):317–36.10.2478/anre-2021-0023Search in Google Scholar

Eckhardt RB, Protsch RR. 1995. Molecular and morphological congruence in hominoid trans-species polymorphisms. Hum Evol 10(3):185–92.10.1007/BF02438970Search in Google Scholar

Eckhardt RB. 1972. Population genetics and human origins. Sci Am 226(1):94–103.10.1038/scientificamerican0172-945061820Search in Google Scholar

Eckhardt RB. 1994. Ape family tree. Nature 372(6504):326.10.1038/372326a07969488Search in Google Scholar

Eckhardt RB. 2003. Polymorphisms past and present. Hum Biol 75(4):559–75.10.1353/hub.2003.005214655877Search in Google Scholar

Foran DR, Hixson JE, Brown WM. 1988. Comparisons of ape and human sequences that regulate mitochondrial DNA transcription and D-loop DNA synthesis. Nucleic Acid Res 16(13):5841–61.10.1093/nar/16.13.5841Search in Google Scholar

Galik K, Senut B, Pickford M, Gommery D, Treil J, Kuperavage AJ, Eckhardt RB. 2004. External and internal morphology of the 1002’00 Orrorin tugenensis femur. Science 305(5689):1450–3.10.1126/science.1098807Search in Google Scholar

Gibbons, A. 1992. Jawing with our Georgian ancestors. Science 255:401.10.1126/science.255.5043.401Search in Google Scholar

Gingerich PD. 1985. Nonlinear molecular clocks and ape-human divergence times. In: PV Tobias, editor. Hominid Evolution: Past, Present and Future. New York: Alan R. Liss. 411–6.Search in Google Scholar

Hasegawa M, Kishino H, Hayasaka K, Horai S. 1990. Mitochondrial DNA evolution in primates: Transition rate has been extremely low in the lemur. J Mol Evol 31(2):113–21.10.1007/BF02109480Search in Google Scholar

Hasegawa M, Kishino H, Taka-aki Y. 1985. Dating of the human-ape splitting by a molecular clock of mitochondrial DNA. J Mol Evol 22(2):160–74.10.1007/BF02101694Search in Google Scholar

Hasegawa M, Kishino H. 1989. Confidence limits on the maximum-likelihood estimate of the hominoid tree from mitochondrial-DNA sequences. Evolution 43:672–7. In: M Kimura, N Takahata, editors. New Aspects of the Genetics of Molecular Evolution. Tokyo: Japan Science Society Press, 303–17.Search in Google Scholar

Hedges SB, Kumar S, Tamura K, Stoneking M. 1991. Human origins and analysis of mitochondrial DNA sequences. Science 255(5045):737–9.10.1126/science.1738849Search in Google Scholar

Higuchi RG, Bowman B, Freiberger M, Ryder OA, Wilson AC. 1989. DNA sequences from the quagga, an extinct member of the horse family. Nature 312(5991):282–4.10.1038/312282a0Search in Google Scholar

Hill A, Ward S, Deino A, Curtis G, Drake R. 1992. Earliest homo. Nature 355(6362):719–22.10.1038/355719a0Search in Google Scholar

Howell N. 1976. Toward a uniformitarian theory of human paleodemography. J Hum Evol 5(1):477–95.10.1016/0047-2484(76)90097-XSearch in Google Scholar

Jin L. 1988 Program for computing the standard errors of nucleotide diversity and nucleotide divergence (SENDFOR). Center for Demographic and Population Genetics, University of Texas Health Science Center, Houston, TX.Search in Google Scholar

Johanson DC, White TD. 1979. A systematic assessment of early African hominids. Science 203(4378):321–30.10.1126/science.104384104384Search in Google Scholar

Jukes T, Cantor CR. 1969. Evolution of protein molecules. In: HN Munro, editor. Mammalian Protein Metabolism. New York: Academic Press. 21–132.10.1016/B978-1-4832-3211-9.50009-7Search in Google Scholar

Kappelman J, Kelley J, Pilbeam D, Sheikh KA, Ward S, Anwar M, Barry JC, Brown B, Hake P Johnson NM, Raza SM, Shah SMI. 1991. The earliest occurrence of Sivapithecus from the middle Miocene Chinji Formation of Pakistan. J Hum Evol 21(1):61–73.10.1016/0047-2484(91)90036-USearch in Google Scholar

Klein RG. 1989. The Human Career: Human Biological and Cultural Origins. 3rd edition. Chicago: University of Chicago Press.Search in Google Scholar

Kocher TD, Wilson AC. 1991. Sequence evolution of mitochondrial DNA in humans and chimpanzees: control region and a protein-coding region. In: S Osawa, T Honjo, editors. Evolution of Life: Fossils, Molecules. Tokyo: Springer-Verlag. 391–413.Search in Google Scholar

Krüger J, Vogel F. 1989. The problem of our common mitochondrial mother. Hum Genet 82(4):308–12.10.1007/BF00273987Search in Google Scholar

MacDougall I. 1981. 40Ar/39Ar age spectra from the KBS Tuff, Koobi Fora Formation Nature 294(5837):120–4.Search in Google Scholar

Maddison DR. 1990. African origin of human mitochondrial DNA reexamined. Syst Zool 40(3):355–63.10.2307/2992327Search in Google Scholar

Marshall BJ. 2005. Helicobacter connections. Nobel Lecture.10.1002/chin.200642258Search in Google Scholar

Nei M, Jin L. 1985. Variances of the average numbers of nucleotide substitutions within and between populations. Mol Biol Evol 6(3):290–300.Search in Google Scholar

Nei M. 1987. Molecular Evolutionary Genetics. New York: Columbia University Press.10.7312/nei-92038Search in Google Scholar

Nei M. 1992. Age of the common ancestor of human mitochondrial DNA. Mol Biol Evol 9(6):1176–8.Search in Google Scholar

Pope GG. 1991. Evolution of the zygomaticomaxillary region in the genusHomo and its relevance to the origin of modern humans. J Hum Evol 21(3):189–213.10.1016/0047-2484(91)90061-YSearch in Google Scholar

Saitou K, Omoto K. 1987. Time and place of human origins from mt DNA data. Nature 327(6120): 288.10.1038/327288a03587346Search in Google Scholar

Saitou N, Nei M. 1987. The neighbor-joining method: A new method for reconstructing phylogenetic trees. Mol Biol Evol 4(4):406–25.Search in Google Scholar

Simons EL. 1967. The significance of primate paleontology for anthropological studies. Am J Phys Anthropol 27(3):307–32.10.1002/ajpa.13302703055591498Search in Google Scholar

Sneath PH, Sokal RR. 1973. Numerical Taxonomy: The Principles and Practice of Numerical Classification. 1st edition. WH Freeman, San Francisco.Search in Google Scholar

Spuhler JN. 1988. Evolution of mitochondrial DNA in monkeys, apes, and humans. Yearb Phys Anthropol 31(59):15–48.10.1002/ajpa.1330310504Search in Google Scholar

Spuhler JN. 1989. Raymond Pearl memorial lecture, 1988: Evolution of mitochondrial DNA in human and other organisms. Am J Hum Biol 1(5):509–28.10.1002/ajhb.131001050328514066Search in Google Scholar

Steininger FF, Rabeder G, Rögl F. 1985. Land mammal distribution in the mediterranean neogene: a consequence of geokinematic and climatic events. In: DJ Stanley, F Wezel, editors. New York: Springer-Verlag. 559–71.Search in Google Scholar

Stoneking M, Cann RL. 1987. African origin of human mitochondrial DNA. IN: PA Mellars, CB Stringer, editors. The Human Revolution: Behavioral and Biological Perspectives on the Origin of Modern Humans. Edinburgh: Edinburgh University Press. 17–30.Search in Google Scholar

Takahata N, Nei M. 1985. Gene genealogy and variance of interpopulational nucleotide differences. Genetics 110(2):325–44.10.1093/genetics/110.2.32512025674007484Search in Google Scholar

Templeton A. 1993. The Eve controversy. Record (Washington University in St. Louis) 17 (April 1, 1993):1 & 6.Search in Google Scholar

Templeton A. 2002. Out of Africa again and again. Nature 416(6876):45–51.10.1038/416045a11882887Search in Google Scholar

Templeton A. 2010. Coherent and incoherent inference in phylogeny and human evolution. Proc of the Natl Acad Sci 107(14):6376–81.10.1073/pnas.0910647107285198820308555Search in Google Scholar

Templeton A. 2018. Human Population Genetics and Genomics. Academic Press.10.1016/B978-0-12-386025-5.00014-2Search in Google Scholar

Templeton AR, Hedges B, Kumar S, Tamura K, Stoneking M. 1992. Human origins and analysis of mitochondrial DNA sequences. Science 255(5045):737–9.10.1126/science.15908491590849Search in Google Scholar

Thorne AG, Wolpoff MH. 1992. The Multiregional Evolution of Humans. Sci Am 266(4):175–9.Search in Google Scholar

Thorne AG, Wolpoff MH. 1981. Regional continuity in Australasian Pleistocene hominid evolution. Am J Phys Antropol 55(3):337–4910.1002/ajpa.13305503086791505Search in Google Scholar

Vigilant L, Pennington R, Harpending H, Kocher TD, Wilson AC. 1989. Mitochondrial DNA sequences in single hairs from a southern African population. PNAS USA 86(23):9350–4.10.1073/pnas.86.23.93502984932594772Search in Google Scholar

Vigilant L, Stoneking M, Harpending H, Hawkes K. 1991. African populations and the evolution of human mitochondrial DNA. Science 253(5027):1503–7.10.1126/science.18407021840702Search in Google Scholar

Ward SC, Brown B, Beecher R. 1989. Craniofacial anatomy of Sivapithecus-Sivalensis based on a reconstruction of GSP 15000. Am J Phys Anthropol 78(2):320–1.Search in Google Scholar

Weidenreich F. 1936. Sinanthropus pekinensis and its position in the line of human evolution. Peking Nat Hist Bull 10:281–90.Search in Google Scholar

Weidenreich F. 1939. Six lectures on Sinanthropus pekinensis and related problems. Bull Geol Soc China 19:64–75.10.1111/j.1755-6724.1939.mp19001005.xSearch in Google Scholar

Weidenreich F. 1940. Some problems dealing with ancient man. Am Anthrop 42(3):375–83.10.1525/aa.1940.42.3.02a00010Search in Google Scholar

Weidenreich F. 1943. The skull of Sinanthropus pekinensis: A comparative study of a primitive hominid skull. Palaeontologia Sinica, New Series D, 10:1–184.Search in Google Scholar

Wilson AC, Stoneking M, Cann RL. 1991. Ancestral geographic states and the peril of parsimony. Syst Zool 40(3):363–5.10.2307/2992328Search in Google Scholar

Wolpoff MH, Thorne AG. 1991. The case against Eve. New Scientist 22(691):33–7.Search in Google Scholar

Wood B. 1992. Origin and evolution of the genus Homo. Nature 355(6363):783–90.10.1038/355783a01538759Search in Google Scholar

Wu X-J, Pei S-W, Cai Y-J, Tong H-W, Li Q, Dong Z, Sheng J-C, Jin Z-T, Ma D-D, et al. 2019. Archaic human remains from Hualongdong, China, and Middle Pleistocene human continuity and variation. PNAS 116(20):9820–4.10.1073/pnas.1902396116652553931036653Search in Google Scholar

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