1. bookVolume 64 (2018): Issue 4 (December 2018)
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04 Apr 2014
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access type Open Access

Analysis of scopoletin and mangiferin in botanicals and formulations of Shankhpushpi by HPLC

Published Online: 04 Mar 2019
Page range: 54 - 62
Received: 02 Apr 2018
Accepted: 15 Oct 2018
Journal Details
License
Format
Journal
First Published
04 Apr 2014
Publication timeframe
4 times per year
Languages
English

Introduction: Shankhpushpi has been widely used in traditional Indian systems of medicine as a brain and memory boosting tonic. There are a variety of botanicals reported to be used as sources of Shankhpushpi in various parts of India. For instance, Canscora decussata Schult, Clitorea ternatea Linn., Convolvulus pluricaulis Choisy. and Evolvulus alsinoides Linn. are most commonly used as sources of Shankhpushpi by practitioners of Ayurveda in different parts of the country.

Keywords

1. Toomula N, Kumar A, Kumar DS, Bheemidi VS. Development and validation of analytical methods for pharmaceuticals. J Anal Bioanal Tech 2011; 2:127. doi: http://dx.doi.org/10.4172/2155-9872.100012710.4172/2155-9872.1000127Open DOISearch in Google Scholar

2. Sethiya NK, Mishra SH. Rapid validated high performance thin layer chromatography method for simultaneous estimation of mangiferin and scopoletin in Canscora decussata (South Indian Shankhpushpi) extract. Revista Brasileira de Farmacognosia 2015; 25:193-198. doi: http://dx.doi.org/10.1016/j.bjp.2015.04.00210.1016/j.bjp.2015.04.002Open DOISearch in Google Scholar

3. Parasuraman S, Thing GS, Dhanaraj SA. Polyherbal formulation: Concept of ayurveda. Pharmacogn Rev 2014; 8 (16):73-80. doi: http://dx.doi.org/10.4103/0973-7847.13422910.4103/0973-7847.134229Open DOISearch in Google Scholar

4. Bhagyasree T, Neelam I, Ajitha A, Rao VUM. A review on analytical method development and validation. Int J Pharm Research Anal 2014; 4(8): 444-448.Search in Google Scholar

5. Archakam SC, Chenchugari S, Banoth CSK. Analytical methods for the recently approved FDA new molecular entities – A review. J Compr Phar 2016; 3(3):70-82.Search in Google Scholar

6. Nahata A, Patil UK, Dixit VK. Effect of Convulvulus pluricaulis Choisy. on learning behaviour and memory enhancement activity in rodents. Nat Prod Res 2008; 22(16):1472-1482. doi: http://dx.doi.org/10.1080/1478641080221419910.1080/14786410802214199Open DOISearch in Google Scholar

7. Nahata A, Patil UK, Dixit VK. Anxiolytic activity of Evolvulus alsinoides and Convulvulus pluricaulis in rodents. Pharmaceut Biol 2009; 47(5): 444-451. doi: http://dx.doi.org/10.1080/1388020090282259610.1080/13880200902822596Open DOISearch in Google Scholar

8. Sethiya NK, Nahata A, Mishra SH, Dixit VK. An update on Shankhpushpi, a cognition-boosting Ayurvedic medicine. J Chin Integr Med 2009; 7(11):1001-1022.Search in Google Scholar

9. Nahata A, Patil UK, Dixit VK. Effect of Evolvulus alsinoides Linn. on learning behavior and memory enhancement activity in rodents. Phytother Res, 2010; 24:486-493. doi: http://dx.doi.org/10.1002/ptr.293210.1002/ptr.2932Open DOISearch in Google Scholar

10. Sethiya NK, Nahata A, Dixit VK. Comparative thin layer chromatographic investigations on sources of Shankhpushpi. Pharmacog J 2009; 1(3):224-226.Search in Google Scholar

11. Sethiya NK, Mishra SH. Investigation of mangiferin, as a promising natural polyphenol xanthone on multiple targets of Alzheimer’s disease. J Biol Act Prod Nat 2014; 4(2): 111-119. doi: http://dx.doi.org/10.1080/22311866.2014.92112110.1080/22311866.2014.921121Open DOISearch in Google Scholar

12. Sethiya NK, Nahata A, Singh PK, Mishra SH. Neuropharmacological evaluation on four traditional herbs used as nervine tonic and commonly available as Shankhpushpi in India. J Ayurveda Integr Med 2017. doi: http://dx.doi.org/10.1016/j.jaim.2017.08.01210.1016/j.jaim.2017.08.012Open DOISearch in Google Scholar

13. Krivut BA, Fedyunina NA, Kocherga SI, Rusakoya SV. Spectrophotometric determination of mangiferin. Chem Nat Compd 1976; 12: 36-38. doi: http://dx.doi.org/10.1007/BF0057017610.1007/BF00570176Open DOISearch in Google Scholar

14. Jubert E, Botha M, Maicu C, De Beer D, Manley M. Rapid screening methods for estimation of mangiferin and xanthone contents of Cyclopia subternata plant material. S Afr J Bot 2012; 82: 113-122. doi: http://dx.doi.org/10.1016/j.sajb.2012.07.01910.1016/j.sajb.2012.07.019Open DOISearch in Google Scholar

15. Nahata a, Dixit VK. Spectrofluorimetric estimation of scopoletin in Evolvulus alsinoides Linn. and Convulvulus pluricaulis Choisy. Indian J Pharm Sci 2008; 70(6): 834-837. doi: http://dx.doi.org/10.4103/0250-474X.4913910.4103/0250-474X.49139Open DOISearch in Google Scholar

16. Sethiya NK, Nahata A, Dixit VK. Simultaneous Spectrofluorimetric determination of scopoletin and mangiferin in a methanolic extract of Canscora decussata Schult. Asian J Trad Med, 2008; 3(6):224-229.Search in Google Scholar

17. Risner CH. The determination of scopoletin in environmental tobacco smoke by high-performance liquid chromatography. J Liq Chromatogr 1994; 17(12): 2723-2736. doi: http://dx.doi.org/10.1080/1082607940801341010.1080/10826079408013410Open DOISearch in Google Scholar

18. Suryawanshi S, Asthana RK, Gupta RC. Simultaneous estimation of mangiferin and four secoiridoid glycosides in rat plasma using liquid chromatography tandem mass spectrometry and its application to pharmacokinetic study of herbal preparation. J Chromatogr B: Anal Technol Biomed Life Sci 2007; 858: 211–219. doi: http://dx.doi.org/10.1016/j.jchromb.2007.08.03410.1016/j.jchromb.2007.08.034Open DOISearch in Google Scholar

19. Upadhyay V, Sharma N, Tiwari AK, Joshi HM, Malik A, Singh B, et al. Standardization of HPLC method of scopoletin in different extracts of Convolvulus pluricaulis. Int J Pharm Sci Drug Res 2013; 5: 28-31.Search in Google Scholar

20. Siddiqui MR, Alothman ZA, Rahman N. Analytical techniques in pharmaceutical analysis: A review. Arab J Chem 2017; 10(1):S1409-1421. doi: http://dx.doi.org/10.1016/j.arabjc.2013.04.01610.1016/j.arabjc.2013.04.016Open DOISearch in Google Scholar

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