1. bookVolume 39 (2018): Issue 2 (July 2018)
Journal Details
License
Format
Journal
eISSN
1576-8597
First Published
30 Jun 2018
Publication timeframe
2 times per year
Languages
English
access type Open Access

Two strategies used to solve a navigation task: A different use of the hippocampus by males and females? A preliminary study in rats

Published Online: 31 Jul 2018
Page range: 319 - 339
Received: 01 Jun 2018
Accepted: 05 Jul 2018
Journal Details
License
Format
Journal
eISSN
1576-8597
First Published
30 Jun 2018
Publication timeframe
2 times per year
Languages
English
Abstract

There is abundant research (both in rodents and in humans) showing that males and females often use different types of information in spatial navigation. Males prefer geometry as a source of information, whereas females tend to focus on landmarks (which are often near to a goal objects). However, when considering the role of the hippocampus, the research focuses primarily on males only. In the present study, based on Rodríguez, Torres, Mackintosh, and Chamizo’s (2010, Experiment 2) navigation protocol, we conducted two experiments, one with males and another with females, in order to tentatively evaluate the role of the dorsal hippocampus in the acquisition of two tasks: one based on landmark learning and the alternate one on local pool-geometry learning. Both when landmark learning and when geometry learning, Sham male rats learned significantly faster than Lesion male animals. This was not the case with female rats in geometry learning. These results suggest that the dorsal hippocampus could play an important role in males only.

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