1. bookTom 22 (2022): Zeszyt 3 (July 2022)
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Pierwsze wydanie
25 Nov 2011
Częstotliwość wydawania
4 razy w roku
access type Otwarty dostęp

Protective effects of dietary Lavender (Lavandula officinalis) essential oil against Malathion-induced toxicity in rainbow trout (Oncorhynchus mykiss)

Data publikacji: 19 Jul 2022
Tom & Zeszyt: Tom 22 (2022) - Zeszyt 3 (July 2022)
Zakres stron: 1087 - 1096
Otrzymano: 12 Oct 2021
Przyjęty: 30 Dec 2021
Informacje o czasopiśmie
Pierwsze wydanie
25 Nov 2011
Częstotliwość wydawania
4 razy w roku

The present study was aimed to evaluate the moderating properties of lavender (Lavandula officinalis) essential oil (LEO) against immunotoxic effects of the organophosphate pesticide, malathion in rainbow trout, Oncorhynchus mykiss. For this purpose, fish were supplemented with LEO at dietary concentrations of 0.5, 1, 2 and 4 ml/kg diet LEO for 56 days. A non-LEO supplemented group was also considered as control. After 57 days feeding trial, biochemicals were assayed in the blood and kidney tissue and then fish exposed to a sub-lethal concentration of malathion [0.24 mg/l equal to 30% of LC50 (0.8 mg/L)]. After 57 days feeding trial, the serum total immunoglobulin, respiratory burst activity, lysozyme activity and complement activity significantly elevated in fish treated with 1 and 2 ml LEO/kg diet compared to non-LEO supplemented individuals (P<0.01). Such changes were not observed in non-LEO supplemented fish (P>0.01). Significant elevations were observed in the expression of the immune genes (iNOS and C3 genes) in fish treated with 0.2–2 mg LEO/kg diet compared to non-supplemented ones (P<0.01). The lysozyme and complement activity significantly decreased in fish fed 4 ml/kg diet (P<0.01). After exposure to malathion, all immune components significantly declined in control and those treated with 0.5, 1 and 4 ml LEO/kg diet (P<0.01). In contrast, the immunity components exhibited no significant changes in fish treated with 2 ml LEO/kg diet after exposure (P>0.01). The expression of iNOS and C3 genes significantly reduced in control and fish fed 0.5, 1 and 4 ml LEO/kg diet in response to malathion (P<0.05). Furthermore, the expression of these genes showed no significant changes in fish fed with 2 ml LEO/kg diet after exposure (P>0.01). The findings of the present study suggested an immunoprotective role for dietary LEO at optimized dietary concentrations of 1 and 2 ml LEO/kg diet against oxidative stress and toxicity induced by malathion. Nevertheless, LEO at high dietary concentration (4 ml/kg diet) had reducing effects on the fish immunity.


Abdel-Latif H.M., Abdel-Daim M.M., Shukry M., Nowosad J., Kucharczyk D. (2021 a). Benefits and applications of Moringa oleifera as a plant protein source in aquafeed: A review. Aquaculture, 737369.10.1016/j.aquaculture.2021.737369 Search in Google Scholar

Abdel-Latif H.M., Hendam B.M., Nofal M.I., El-Son M.A. (2021 b). Ginkgo biloba leaf extract on improves growth, intestinal histomorphometry, immunity, antioxidant status and modulates transcription of cytokine genes in hapa-reared Oreochromis niloticus. Fish. Shellfish. Immunol., 117: 339–349.10.1016/j.fsi.2021.06.00334153429 Search in Google Scholar

Abid-Essefi S., Zaied C., Bouaziz C., Salem I.B., Kaderi R., Bacha H. (2012). Protective effect of aqueous extract of Allium sativum against zearalenone toxicity mediated by oxidative stress. Exp. Toxicol. Pathol., 64: 689–695. Search in Google Scholar

Agbohessi P.T., Toko I.I., Atchou V., Tonato R., Mandiki S.N.M., Kestemont P. (2015). Pesticides used in cotton production affect reproductive development, endocrine regulation, liver status and offspring fitness in African catfish Clarias gariepinus (Burchell, 1822). Com. Biochem. Physiol Part C: Toxicol. Pharmacol., 167: 157–172. Search in Google Scholar

Ahmadi K., Mirvaghefei A.R., Banaee M., Vosoghei A.R. (2014). Effects of long-term malathion exposure on some immunological and haematological parameters in rainbow trout Oncorhynchus mykiss (Walbaum, 1792). Toxicol. Environ. Health. Sci., 6: 1–7. Search in Google Scholar

Al-Shawi S.G., Al-Younis Z.K., Abd Al-Kareem N.F. (2017). Study of cumin antibacterial and antioxidant activity of alcoholic and aqueous extracts. Pak. J. Biotechnol., 14: 227–231. Search in Google Scholar

Awad E., Mitchell W.J., Austin B. (2011). Effect of dietary supplements on cytokine gene expression in rainbow trout, Oncorhynchus mykiss (Walbaum). J. Fish. Dis., 34: 629–634. Search in Google Scholar

Banaee M., Mirvagefei A.R., Rafei G.R., Majazi Amiri B. (2008). Effect of sub-lethal malathion concentrations on blood plasma biochemistry. Int. J. Environ. Res., 2: 189–198. Search in Google Scholar

Banaee M., Sureda A., Mirvaghefi A.R., Ahmadi K. (2011). Effects of malathion on biochemical parameters of blood in rainbow trout (Oncorhynchus mykiss). Pes. Biochem. Physiol., 99: 1–6. Search in Google Scholar

Banaee M., Sureda A., Shahaf S., Fazilat N. (2015). Protective effects of silymarin extract on malthion-induced zebra cichlid (Cichlasomanigro fasciatum) hepatotoxicity. Iran. J. Toxicol., 928: 1239–1246. Search in Google Scholar

Bols N.C., Brubacher J.L., Ganassin R.C., Lee L.E. (2001). Ecotoxicology and innate immunity in fish. Develop. Com. Immunol., 25: 853–873. Search in Google Scholar

Cardia G.F.E., Silva-Filho S.E., Silva E.L., Uchida N.S., Cavalcante H.A.O., Cassarotti L.L., Salvadego V.E.C., Spironello R.A., Bersani-Amado C.A., Cuman R.K.N. (2018). Effect of lavender (Lavandula angustifolia) essential oil on acute inflammatory response. Evidence-Base. Compl. Alter. Med., 2018: 1–10. Search in Google Scholar

Chakraborty S.B., Hancz C. (2011). Application of phytochemicals as immunostimulant, antipathogenic and antistress agents in finfish culture. Rev. Aquacult., 3: 103–119. Search in Google Scholar

Chipman D.M., Sharon N. (1969). Mechanism of lysozyme action. Science, 165: 454–465. Search in Google Scholar

Ciftci O., Ozdemir I., Tanyildizi S., Yildiz S., Oguzturk H. (2011). Antioxidative effects of curcumin, β-myrcene and 1, 8-cineole against 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced oxidative stress in rats liver. Toxicol. Indus. Health., 27: 447–453. Search in Google Scholar

Citarasu T., Venket Ramalingam K., Raja Jeya Sekar R., Micheal Babu M., Marian M.P. (2002). Influence of the antibacterial herbs, Solanum trilobatum, Andrographis paniculata and Psoralea corylifolia on the survival, growth and bacterial load of Penaeus monodon post larvae. Aquacult. Int., 11: 583–595. Search in Google Scholar

Dawood M.A., Metwally A.E.S., Elkomy A.H., Gewaily M.S., Abdo S.E., Abdel-Razek M.A., Soliman A.A., Amer A.A., Abdel-Razik N.I., Abdel-Latif H.M.R., Paray B.A. (2020 a). The impact of menthol essential oil against inflammation, immunosuppression, and histopathological alterations induced by chlorpyrifos in Nile tilapia. Fish. Shellfish Immunol., 102: 316–325.10.1016/j.fsi.2020.04.05932371257 Search in Google Scholar

Dawood M.A., Abdel-Tawwab M., Abdel-Latif H.M. (2020 b). Lycopene reduces the impacts of aquatic environmental pollutants and physical stressors in fish. Rev. Aquacult., 12: 2511–2526.10.1111/raq.12455 Search in Google Scholar

De Silva P.M.C.S., Samayawardhena L.A. (2005). Effects of chlorpyrifos on reproductive performances of guppy (Poecilia reticulata). Chemosphere, 58: 1293–1299. Search in Google Scholar

Denslow N., Sepúlveda M. (2007). Ecotoxicological effects of endocrine disrupting compounds on fish reproduction. Springer, Dordrecht. Fish Oocyte, pp. 255–322.10.1007/978-1-4020-6235-3_10 Search in Google Scholar

Díaz-Resendiz K.J.G., Girón-Pérez M.I. (2014). Effect of chlorpyrifos on the immune response of Nile tilapia (Oreochromis niloticus). Conacyt. Zagazig. Vet. J., 44: 196–204. Search in Google Scholar

Dügenci S.K., Arda N., Candan A. (2003). Some medicinal plants as immunostimulant for fish. J. Ethnopharmacol., 88: 99–106. Search in Google Scholar

El-Boshy M., Ashshi A., Gaith M., Qusty N., Bokhary T., AlTaweel N., Abdelhady M. (2017). Studies on the protective effect of the artichoke (Cynara scolymus) leaf extract against cadmium toxicity-induced oxidative stress, hepatorenal damage, and immunosuppressive and hematological disorders in rats. Environ. Sci. Poll. Res., 24: 12372–12383. Search in Google Scholar

El-Gendy K.S., Aly N.M., El-Sebae A.H. (1998). Effects of edifenphos and glyphosate on the immune response and protein biosynthesis of bolti fish (Tilapia nilotica). J. Environ. Sci. Health. Part B, 33: 135–149. Search in Google Scholar

El-Hameed A., Samah A.A., Negm S.S., Ismael N.E., Naiel M.A., Soliman M.M., Shukry M., Abdel-Latif H.M. (2021). Effects of activated charcoal on growth, immunity, oxidative stress markers, and physiological responses of Nile tilapia exposed to sub-lethal imidacloprid toxicity. Animal, 11: 1357. Search in Google Scholar

El Mehiry H.F., Shelbaya L.A. (2019). Immunotoxicity effect of lavender (Lavendula spica) flowers powder and oil on azathioprine induced toxicity in experimental rats. J. Stud. Search. Spec. Educ., 2: 219–233. Search in Google Scholar

Farag M.R., Alagawany M., Bilal R.M., Gewida A.G., Dhama K., Abdel-Latif H.M., Amer M.S., Rivero-Perez N., Zaragoza-Bastida A., Binnaser Y.S., El-Saber Batiha G., Naiel M.A.E. (2021 a). An overview on the potential hazards of pyrethroid insecticides in fish, with special emphasis on cypermethrin toxicity. Animals, 11: 1880.10.3390/ani11071880830035334201914 Search in Google Scholar

Farag M.R., Alagawany M., Khalil S.R., Moustafa A.A., Mahmoud H.K., Abdel-Latif H.M. (2021 b). Astragalus membranaceus polysaccharides modulate growth, hemato-biochemical indices, hepatic antioxidants, and expression of HSP70 and apoptosis-related genes in Oreochromis niloticus exposed to sub-lethal thallium toxicity. Fish. Shellfish. Immunol., 118: 251–260.10.1016/j.fsi.2021.09.00934509627 Search in Google Scholar

Fatima M., Mandiki S.N.M., Douxfils J., Silvestre F., Coppe P., Kestemont P. (2007). Combined effects of herbicides on biomarkers reflecting immune–endocrine interactions in goldfish: immune and antioxidant effects. Aquatic. Toxicol., 81: 159–167. Search in Google Scholar

Fazio A., Cerezuela R., Panuccio M.R., Cuesta A., Esteban M.Á. (2017). In vitro effects of Italian Lavandula multifida L. leaf extracts on gilthead seabream (Sparus aurata) leucocytes and SAF-1 cells. Fish Shellfish Immunol., 66: 334–344. Search in Google Scholar

Gashi F., Dreshaj E., Troni N., Maxhuni A., Laha F. (2020). Determination of heay metal contents in water of Llapi River (Kosovo). A case study of correlations coefficients. Europ. Chem. Bull., 9: 43–47. Search in Google Scholar

Ghafari Farsani H., Hedayati S.A., Zare Nadimi Bin N., Azizpour S., Shahbazi Naserabad S. (2016 a). Effects of sub lethal concentrations of pesticide malathion on hematology parameters of rainbow trout (Oncorhynchus mukiss). J. Oceanograph., 7: 1–9. Search in Google Scholar

Ghafari Farsani H., Poorbagher H., Farahmand H. (2016 b). Effects of malathion on DNA breakage in the liver and gill of rainbow trout (Oncorhynchus mykiss) using weighted averaging. J. Fish, 69: 89–99. Search in Google Scholar

Ghafarifarsani H., Hoseinifar S.H., Aftabgard M., Van Doan H. (2022). The improving role of savory (Satureja hortensis) essential oil for Caspian roach (Rutilus caspicus) fry: Growth, haematological, immunological, and antioxidant parameters and resistance to salinity stress. Aquaculture, 548: 737653. Search in Google Scholar

Ghasemzadeh J., Sinaei M., Bolouki M. (2015). Biochemical and histological changes in fish, spotted scat (Scatophagus argus) exposed to malathion. Bull. Environ. Contamin. Toxicol., 94: 164–170. Search in Google Scholar

Girón-Pérez M.I., Santerre A., Gonzalez-Jaime F., Casas-Solis J., Hernández-Coronado M., Peregrina-Sandoval J., Takemura A., Zaitseva G. (2007). Immunotoxicity and hepatic function evaluation in Nile tilapia (Oreochromis niloticus) exposed to malathion. Fish. Shellfish. Immunol., 23: 760–769. Search in Google Scholar

Gülçin Ì., Şat İ.G., Beydemir Ş., Elmastaş M., Küfrevioǧlu Ö.İ. (2004). Comparison of antioxidant activity of clove (Eugenia caryophylata Thunb) buds and lavender (Lavandula stoechas L.). Food. Chem., 87: 393–400. Search in Google Scholar

Hajirezaee S., Hossein Khanjani M. (2021). Evaluation of dietary inclusion of Bunium persicum, Bunium persicum essential oil on growth, immune components, immune-related gene expressions and resistance to Aeromonas hydrophila, in rainbow trout, Oncorhynchus mykiss. Aquacult. Res., 52: 4711–4723. Search in Google Scholar

Hajirezaee S., Mirvaghefi A.R., Farahmand H., Agh N. (2016). Effects of malathion on adaptation to sea-water by the endangered Persian sturgeon, Acipenser persicus, fingerlings. Ecotoxicol. Environ. Safety, 133: 413–423. Search in Google Scholar

Hajirezaee S., Rafieepour A., Shafiei S. (2019 a). A NMR-based metabonomic study on the ameliorating effects of Ginkgo biloba extract in rainbow trout, Oncorhynchus mykiss exposed to organophosphate pesticide, diazinon. Aquaculture, 513: 734450.10.1016/j.aquaculture.2019.734450 Search in Google Scholar

Hajirezaee S., Rafieepour A., Shafiei S., Rahimi R. (2019 b). Immunostimulating effects of Ginkgo biloba extract against toxicity induced by organophosphate pesticide, diazinon in rainbow trout, Oncorhynchus mykiss: innate immunity components and immune-related genes. Environ. Sci. Poll. Res., 26: 8798–8807.10.1007/s11356-019-04327-730712205 Search in Google Scholar

Hajirezaee S., Abed-Elmdoust A., Alekhina N., Chupradit S., Mustafa Y.F. (2021). Metabolite profiling of the post-ovulatory oocytes of the common carp, Cyprinus carpio: A 1H NMR-based metabolomics approach. Com. Biochem. Physiol. Part D: Genom. Proteom., 40: 100917. Search in Google Scholar

Halim S., Mohamad N., Ridzuan P.M., Zakaria N.H., Muhammad N.A. (2019). In-vitro study: Camp overshoot caused by chronic morphine alleviated by the synergistic combination of Zamzam water and methadone in human primary Glioblastoma cell line (U-87 MG). IIUM Med. J. Malaysia., 18: 47–52. Search in Google Scholar

Hassanalizadeh Chari F., Akrami R., Ghelichi A., Ebrahimi P. (2020). The effect of Lavandula officinalis nanoemulsion on growth performance, body composition, haematology and immunity parameters of Oncorhynchus mykiss. J. Appl. Anim. Res., 48: 340–347. Search in Google Scholar

Hedayati S.A.A., Ghafari Farsani H., Shahbazi Naserabad S., Gerami M.H. (2015). Acute toxicity and behavioral changes associated with diazinon in Rutilus rutilus caspicus and Hypophthalmicthys molitrix. Iran. J. Toxicol., 9: 1354–1359. Search in Google Scholar

Ibrahem A.A., Al-Temimi W.K.A., Al-Shawi S.G. (2021). The optimum conditions for fructooligosaccharide production by using crude fructosyltransferase of plant origin. Plant Cell. Biothechnol. Mol. Biol., 22: 252–265. Search in Google Scholar

Islam M.S., Tanaka M. (2004). Impacts of pollution on coastal and marine ecosystems including coastal and marine fisheries and approach for management: a review and synthesis. Mar. Poll. Bull., 48: 624–649. Search in Google Scholar

Ismael N.E., Abd El-hameed S.A., Salama A.M., Naiel M.A., Abdel-Latif H.M. (2021). The effects of dietary clinoptilolite and chitosan nanoparticles on growth, body composition, haemato-biochemical parameters, immune responses, and antioxidative status of Nile tilapia exposed to imidacloprid. Environ. Sci. Poll. Res. Int., 28: 29535–29550. Search in Google Scholar

Juergens U.R. (2014). Anti-inflammatory properties of the monoterpene 1.8-cineole: current evidence for co-medication in inflammatory airway diseases. Drug. Res., 64: 638–646. Search in Google Scholar

Katuli K.K., Amiri B.M., Massarsky A., Yelghi S. (2014). Impact of a short-term malathion exposure on the osmoregulation potentiality of Caspian roach (Rutilus rutilus) fingerlings. Chemosphere, 108: 396–404. Search in Google Scholar

Khafaga A.F., Naiel M.A., Dawood M.A., Abdel-Latif H.M. (2020). Dietary Origanum vulgare essential oil attenuates cypermethrin-induced biochemical changes, oxidative stress, histopathological alterations, apoptosis, and reduces DNA damage in common carp (Cyprinus carpio). Aquatic. Toxicol., 228: 105624. Search in Google Scholar

Khalil S.R., Abd Elhakim Y., Abd El-Fattah A.H., Farag M.R., Abd El-Hameed N.E., Abd Elhakeem E.M. (2020). Dual immunological and oxidative responses in Oreochromis niloticus fish exposed to lambda cyhalothrin and concurrently fed with thyme powder (Thymus vulgaris L.): Stress and immune encoding gene expression. Fish. Shellfish. Immunol., 100: 208–218. Search in Google Scholar

Khan M.Z., Law F.C. (2005). Adverse effects of pesticides and related chemicals on enzyme and hormone systems of fish, amphibians and reptiles: a review. Proc. Pak. Acad. Sci., 42: 315–323. Search in Google Scholar

Khan J., Kusmahani S.H., Ruhi S., Al-Dhalli S., Kaleemullah M., Saad R., et al. (2020 a). Design and evaluation of sustained release matrix tablet of flurbiprofen by using hydrophilic polymer and natural gum. J. Med. Toxicol. Legal Med., 23: 149–159.10.5958/0974-4614.2020.00025.X Search in Google Scholar

Khan J., Leenoos L.M., Ruhi S., Al-Dhalli S., Kaleemullah M., Saad R., et al. (2020 b). Development and evaluation of polyherbal halal ointment using honey and Papaya. J. Med. Toxicol. Legal Med., 23: 232–238.10.5958/0974-4614.2020.00033.9 Search in Google Scholar

Khoshbavar-Rostami H.A., Soltani M., Hassan H.M.D. (2006). Immune response of great sturgeon (Huso huso) subjected to long-term exposure to sublethal concentration of the organophosphate, malathion. Aquaculture, 256: 88–94. Search in Google Scholar

Kookana R.S., Correll R.L., Miller R.B. (2005). Pesticide impact rating index – a pesticide risk indicator for water quality. Water Air Soil Pollut. Focus, 5: 45–65. Search in Google Scholar

Kreutz L.C., Barcellos L.J.G., de Faria Valle S., de Oliveira Silva T., Anziliero D., dos Santos E. D., Pivato M., Zanatta R. (2011). Altered hematological and immunological parameters in silver catfish (Rhamdia quelen) following short term exposure to sublethal concentration of glyphosate. Fish. Shellfish Immunol., 30: 51–57. Search in Google Scholar

Li X., Liu L., Zhang Y., Fang Q., Li Y., Li Y. (2013). Toxic effects of chlorpyrifos on lysozyme activities, the contents of complement C3 and IgM, and IgM and complement C3 expressions in common carp (Cyprinus carpio L.). Chemosphere, 93: 428–433. Search in Google Scholar

Ma J., Li X. (2015). Alteration in the cytokine levels and histopathological damage in common carp induced by glyphosate. Chemosphere, 128: 293–298. Search in Google Scholar

Mashoof S., Criscitiello M.F. (2016). Fish immunoglobulins. Biology, 5: 45. Search in Google Scholar

Miandare H.K., Farahmand H., Akbarzadeh A., Ramezanpour S., Kaiya H., Miyazato M., Rytkönen K., Nikinmaa M. (2013). Developmental transcription of genes putatively associated with growth in two sturgeon species of different growth rate. Gen. Com. Endocrinol., 182: 41–47. Search in Google Scholar

Mirghaed A.T., Hoseini S.M., Ghelichpour M. (2018). Effects of dietary 1, 8-cineole supplementation on physiological, immunological and antioxidant responses to crowding stress in rainbow trout (Oncorhynchus mykiss). Fish. Shellfish Immunol., 81: 182–188. Search in Google Scholar

Mohamed M.F., Ahmed N.M., Fathy Y.M., Abdelhamid I.A. (2020). Impact of heavy metals on Oreochromis niloticus fish and using electrophoresis as bio-indicator for environmental pollution of Rosetta btanch, River Nile, Egypt. Europ. Chem. Bull., 9: 48–61. Search in Google Scholar

Mondon J.A., Duda S., Nowak B.F. (2000). Immune response of greenback flounder Rhombosolea tapirina after exposure to contaminated marine sediment and diet. Mar. Environ. Res., 50: 443–450. Search in Google Scholar

Naiel M.A., Ismael N.E., Abd El-Hameed S.A., Amer M.S. (2020). The antioxidative and immunity roles of chitosan nanoparticle and vitamin C-supplemented diets against imidacloprid toxicity on Oreochromis niloticus. Aquaculture, 523: 735219. Search in Google Scholar

Nayak A.S., Lage C.R., Kim C.H. (2007). Effects of low concentrations of arsenic on the innate immune system of the zebrafish (Danio rerio). Toxicol. Sci., 98: 118–124. Search in Google Scholar

Olutayo M., Friday J.N. (2020). Evaluation of organic substrates for outdoor cultivation of Pleurotus tuber-regium. Int. J. Biotechnol., 9: 8–13. Search in Google Scholar

Othman Z., Khalep H.R.H., Abidin A.Z., Hassan H., Fattepur S. (2019). The anti-angiogenic properties of Morinda citrifolia L. (Mengkudu) leaves using chicken chorioallantoic membrane (CAM) assay. Pharmacog. J., 11: 12–15. Search in Google Scholar

Peana A.T., D’Aquila P.S., Panin F., Serra G., Pippia P., Moretti M.D.L. (2002). Anti-inflammatory activity of linalool and linalyl acetate constituents of essential oils. Phytomedicine, 9: 721–726. Search in Google Scholar

Pinmongkhonkul S., Khamkhunmuang T., Madhayamapurush W. (2021). Ethnobotanical study and plant dimension classification in Kwan Phayao community areas, Phayao Province, Thailand. AgBioForum, 23: 65–71. Search in Google Scholar

Poorbagher H., Ghaffari Farsani H., Farahmand H. (2018). A method to quantify genotoxicity of malathion in rainbow trout using the weighted averaging. Toxicol. Mechanic. Method., 28: 607–614. Search in Google Scholar

Prasad S., Variyur Padhyoy K.B. (1993). Chemical investigation of some commonly used spices. Aryavaidyan, 6: 262–267. Search in Google Scholar

Rabie M., Asri Y., Ahmadi K. (2016). Effect of milk thistle plant, Vitis vinifera extract on immune system of rainbow trout (Oncorhynchus mykiss) challenge by malathion. Int. J. Aqua. Biol., 4: 208. Search in Google Scholar

Rafieepour A., Hajirezaee S., Rahimi R. (2019 a). Dietary oregano extract (Origanum vulgare L.) enhances the antioxidant defence in rainbow trout, Oncorhynchus mykiss against toxicity induced by organophosphorus pesticide, diazinon. Toxin Rev., 39: 397–407.10.1080/15569543.2018.1550092 Search in Google Scholar

Rafieepour A., Hajirezaee S., Rahimi R. (2019 b). Moderating effects of dietary oregano extract (Origanum vulgare) on the toxicity induced by organophosphate pesticide, diazinon in rainbow trout, Oncorhynchus mykiss: metabolic hormones, histology and growth parameters. Turk. J. Fish. Aqua. Sci., 20: 207–219. Search in Google Scholar

Ramsden C.S., Smith T.J., Shaw B.J., Handy R.D. (2009). Dietary exposure to titanium dioxide nanoparticles in rainbow trout (Oncorhynchus mykiss): no effect on growth, but subtle biochemical disturbances in the brain. Ecotoxicology, 18: 939–951. Search in Google Scholar

Rao J.V., Rani C.S., Kavitha P., Rao R.N., Madhavendra S.S. (2003). Toxicity of chlorpyrifos to the fish Oreochromis mossambicus. Bull. Environ. Contamin. Toxicol., 70: 0985–0992. Search in Google Scholar

Raymond M. (1985). Log-probit analysis program presentation for a microcomputer. Entomologie Médicale et Parasitologie, 23: 117–121. Search in Google Scholar

Raza S.H.A., Naqvi S.R.Z., Abdelnour S.A., Schreurs N., Mohammedsaleh Z.M., Khan I., Shater A.F., Abd El-Hack M.E., Khafaga A.F., Quan G., Zan L. (2021). Beneficial effects and health benefits of astaxanthin molecules on animal production: A review. Res. Vet. Sci., 138: 69–78. Search in Google Scholar

Raza S.H., Abdelnour S.A., Alotaibi M.A., AlGabbani Q., Naiel M.A., Shokrollahi B., Noreldin A.E., Jahejo A.R., Zhang H., Alagawany M., Zan L. (2022). MicroRNAs mediated environmental stress responses and toxicity signs in teleost fish species. Aquaculture, 737310.10.1016/j.aquaculture.2021.737310 Search in Google Scholar

Reverter M., Bontemps N., Lecchini D., Banaigs B., Sasal P. (2014). Use of plant extracts in fish aquaculture as an alternative to chemotherapy: current status and future perspectives. Aquaculture, 433: 50–61. Search in Google Scholar

Ridzuan P.M., Alaina H.Y., Atika A.R., Nazira C.M., Afrina A., Alya-Syarafina M.S., Mujahid M.S., Shariff M.H.B.M. (2019). The efficacy of Piper aduncum extract as natural larvicides against Aedes aegypti larvae. Int. J. Med. Toxicol. Legal Med., 22: 154–159. Search in Google Scholar

Rooijakkers S.H., van Strijp J.A. (2007). Bacterial complement evasion. Mol. Immunol., 44: 23–32. Search in Google Scholar

Roslan N., Shariff H. (2019). Potential pharmacotherapy of Olea europaea (olive) fruit oil against neurotoxicity induced methamphetamine. J. Cell. Mol. Anesthesia, 2: 67–68. Search in Google Scholar

Saurabh S., Sahoo P.K. (2008). Lysozyme: an important defence molecule of fish innate immune system. Aquacult. Res., 39: 223–239. Search in Google Scholar

Secombes C.J., Fletcher T.C. (1992). The role of phagocytes in the protective mechanisms of fish. Ann. Rev. Fish. Dis., 2: 53–71. Search in Google Scholar

Selmi S., Jallouli M., Gharbi N., Marzouki L. (2015). Hepatoprotective and renoprotective effects of lavender (Lavandula stoechas L.) essential oils against malathion-induced oxidative stress in young male mice. J. Med. Food., 18: 1103–1111. Search in Google Scholar

Shahbazi Naserabad S., Mirvaghefi A., Gerami M.H., Ghafari Farsani H. (2015). Acute toxicity and behavioral changes of the gold fish (Carassius auratus) exposed to malathion and hinosan. Iran. J. Toxicol., 8: 1203–1208. Search in Google Scholar

Shelley L.K., Balfry S.K., Ross P.S.., Kennedy C.J. (2009). Immunotoxicological effects of a sub-chronic exposure to selected current-use pesticides in rainbow trout (Oncorhynchus mykiss). Aqua. Toxicol., 92: 95–103. Search in Google Scholar

Sivaram Jian J., Wu Z. (2004). Effect of Chinese herbal medicine on non-specific immunity of Jian common carp (Cyprinus carpio var. Jian). J. Dalian. Fish. Univ., 17: 114–119. Search in Google Scholar

Siwicki A.K., Terech-Majewska E., Grudniewska J., Malaczewska J., Kazun K., Lepa A. (2010). Influence of deltamethrin on nonspecific cellular and humoral defense mechanisms in rainbow trout (Oncorhynchus mykiss). Environ. Toxicol. Chem., 29: 489–491. Search in Google Scholar

Slaninova A., Smutna M., Modra H., Svobodova Z. (2009). A review: Oxidative stress in fish induced by pesticides. Neuroendocrinol. Lett., 30: 2. Search in Google Scholar

Tukmechi A., Rezaee J., Nejati V., Sheikhzadeh N. (2014). Effect of acute and chronic toxicity of paraquat on immune system and growth performance in rainbow trout, Oncorhynchus mykiss. Aquacult. Res., 45: 1737–1743. Search in Google Scholar

Uribe C., Folch H., Enriquez R., Moran G. (2011). Innate and adaptive immunity in teleost fish: a review. Vet. Med., 56: 486–503. Search in Google Scholar

Velisek J., Svobodova Z., Machova J. (2009). Effects of bifenthrin on some haematological, biochemical and histopathological parameters of common carp (Cyprinus carpio L.). Fish Physiol. Biochem., 35: 583–590. Search in Google Scholar

Velmurugan B., Selvanayagam M., Cengiz E.I., Unlu E. (2009). Histopathological changes in the gill and liver tissues of freshwater fish, Cirrhinus mrigala exposed to dichlorvos. Brazil. Arch. Biol. Technol., 52: 1291–1296. Search in Google Scholar

Vymazal J., Březinová T. (2015). The use of constructed wetlands for removal of pesticides from agricultural runoff and drainage: a review. Environ. Int., 75: 11–20. Search in Google Scholar

Wagner E., Arndt R., Hilton B. (2002). Physiological stress responses, egg survival and sperm motility for rainbow trout broodstock anesthetized with clove oil, tricaine methanesulfonate or carbon dioxide. Aquaculture, 211: 353–366. Search in Google Scholar

Wulandari A.P., Haifa I.H., Ratnaniati D., Rossiana N. (2021). Bactericidal activity of extracts and major fractions of endophyte metabolites of fungus Cladosporium velox against pneumonia and diarrhea pathogens. AgBioForum, 23: 84–91. Search in Google Scholar

Yousefi M., Hoseinifar S.H., Ghelichpour M., Hoseini S.M. (2018). Anesthetic efficacy and biochemical effects of citronellal and linalool in common carp (Cyprinus carpio Linnaeus, 1758) juveniles. Aquaculture, 493: 107–112. Search in Google Scholar

Yousefi M., Shabunin S.V., Vatnikov Y.A., Kulikov E.V., Adineh H., Hamidi M.K., Hoseini S.M. (2020). Effects of lavender (Lavandula angustifolia) extract inclusion in diet on growth performance, innate immunity, immune gene expression, and stress response of common carp, Cyprinus carpio. Aquaculture, 515: 734588. Search in Google Scholar

Zahran E., Risha E., Awadin W., Palić D. (2018). Acute exposure to chlorpyrifos induces reversible changes in health parameters of Nile tilapia (Oreochromis niloticus). Aqua. Toxicol., 197: 47–59. Search in Google Scholar

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