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Effect of the oral intake of astaxanthin on semen parameters in patients with oligo-astheno-teratozoospermia: a randomized double-blind placebo-controlled trial


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Sharlip ID, Jarow JP, Belker AM, Lipshultz LI, Sigman M, Thomas AJ, et al. Best practice policies for male infertility. Fertil Steril 2002; 77: 873-82. doi: 10.1016/s0015-0282(02)03105-9SharlipIDJarowJPBelkerAMLipshultzLISigmanMThomasAJet alBest practice policies for male infertilityFertil Steril2002778738210.1016/s0015-0282(02)03105-9Open DOISearch in Google Scholar

Cooper TG, Noonan E, von Eckardstein S, Auger J, Baker HW, Behre HM, et al. World Health Organization reference values for human semen characteristics. Hum Reprod Update 2010; 16: 231-45. doi: 10.1093/humupd/dmp048CooperTGNoonanEvon EckardsteinSAugerJBakerHWBehreHMet alWorld Health Organization reference values for human semen characteristicsHum Reprod Update2010162314510.1093/humupd/dmp04819934213Open DOISearch in Google Scholar

Desai N, Sharma R, Makker K, Sabanegh E, Agarwal A. Physiologic and pathologic levels of reactive oxygen species in neat semen of infertile men. Fertil Steril 2009; 92: 1626-31. doi: 10.1016/j.fertnstert.2008.08.109DesaiNSharmaRMakkerKSabaneghEAgarwalAPhysiologic and pathologic levels of reactive oxygen species in neat semen of infertile menFertil Steril20099216263110.1016/j.fertnstert.2008.08.10918937945Open DOISearch in Google Scholar

Rivlin J, Mendel J, Rubinstein S, Etkovitz N, Breitbart H. Role of hydrogen peroxide in sperm capacitation and acrosome reaction. Biol Reprod 2004; 70: 518-22. doi: 10.1095/biolreprod.103.020487RivlinJMendelJRubinsteinSEtkovitzNBreitbartHRole of hydrogen peroxide in sperm capacitation and acrosome reactionBiol Reprod2004705182210.1095/biolreprod.103.02048714561655Open DOISearch in Google Scholar

Agarwal A, Virk G, Ong C, du Plessis SS. Effect of oxidative stress on male reproduction. World J Mens Health 2014; 32: 1-17. doi: 10.5534/wjmh.2014.32.1.1AgarwalAVirkGOngCduPlessis SSEffect of oxidative stress on male reproductionWorld J Mens Health20143211710.5534/wjmh.2014.32.1.1402622924872947Open DOISearch in Google Scholar

Darbandi M, Darbandi S, Agarwal A, Sengupta P, Durairajanayagam D, Henkel R, et al. Reactive oxygen species and male reproductive hormones. Reprod Biol Endocrinol 2018; 16: 87. doi: 10.1186/s12958-018-0406-2DarbandiMDarbandiSAgarwalASenguptaPDurairajanayagamDHenkelRet alReactive oxygen species and male reproductive hormonesReprod Biol Endocrinol2018168710.1186/s12958-018-0406-2613450730205828Open DOISearch in Google Scholar

Gosalvez J, Tvrda E, Agarwal A. Free radical and superoxide reactivity detection in semen quality assessment: past, present, and future. J Assist Reprod Genet 2017; 34: 697-707. doi: 10.1007/s10815-017-0912-8GosalvezJTvrdaEAgarwalAFree radical and superoxide reactivity detection in semen quality assessment: past, present, and futureJ Assist Reprod Genet20173469770710.1007/s10815-017-0912-8544504928341974Open DOISearch in Google Scholar

Kao SH, Chao HT, Chen HW, Hwang TI, Liao TL, Wei YH. Increase in oxidative stress in human sperm with lower motility. Fertil Steril 2008; 89: 1183-90. doi: 10.1016/j.fertnstert.2007.05.029KaoSHChaoHTChenHWHwangTILiaoTLWeiYHIncrease in oxidative stress in human sperm with lower motilityFertil Steril20088911839010.1016/j.fertnstert.2007.05.02917669405Open DOISearch in Google Scholar

Agarwal A, Ahmad G, Sharma R. Reference values of reactive oxygen species in seminal ejaculates using chemiluminescence assay. J Assist Reprod Genet 2015; 32: 1721-9. doi: 10.1007/s10815-015-0584-1AgarwalAAhmadGSharmaRReference values of reactive oxygen species in seminal ejaculates using chemiluminescence assayJ Assist Reprod Genet2015321721910.1007/s10815-015-0584-1468173626431955Open DOISearch in Google Scholar

Aitken RJ, De Iuliis GN, Finnie JM, Hedges A, McLachlan RI. Analysis of the relationships between oxidative stress, DNA damage and sperm vitality in a patient population: development of diagnostic criteria. Hum Reprod 2010; 25: 2415-26. doi: 10.1093/humrep/deq214AitkenRJDeIuliis GNFinnieJMHedgesAMcLachlanRIAnalysis of the relationships between oxidative stress, DNA damage and sperm vitality in a patient population: development of diagnostic criteriaHum Reprod20102524152610.1093/humrep/deq21420716559Open DOISearch in Google Scholar

Verit FF, Verit A, Kocyigit A, Ciftci H, Celik H, Koksal M. No increase in sperm DNA damage and seminal oxidative stress in patients with idiopathic infertility. Arch Gynecol Obstet 2006; 274: 339-44. doi: 10.1007/s00404-006-0172-9VeritFFVeritAKocyigitACiftciHCelikHKoksalMNo increase in sperm DNA damage and seminal oxidative stress in patients with idiopathic infertilityArch Gynecol Obstet20062743394410.1007/s00404-006-0172-9Open DOISearch in Google Scholar

Aitken RJ, Clarkson JS, Fishel S. Generation of reactive oxygen species, lipid peroxidation, and human sperm function. Biol Reprod 1989; 41: 183-97. doi: 10.1095/biolreprod41.1.183AitkenRJClarksonJSFishelSGeneration of reactive oxygen species, lipid peroxidation, and human sperm functionBiol Reprod1989411839710.1095/biolreprod41.1.183Open DOISearch in Google Scholar

Agarwal A, Saleh RA, Bedaiwy MA. Role of reactive oxygen species in the pathophysiology of human reproduction. Fertil Steril 2003; 79: 829-43. doi: 10.1016/s0015-0282(02)04948-8AgarwalASalehRABedaiwyMARole of reactive oxygen species in the pathophysiology of human reproductionFertil Steril2003798294310.1016/s0015-0282(02)04948-8Open DOISearch in Google Scholar

Jacobsen R, Bostofte E, Engholm G, Hansen J, Olsen JH, Skakkebaek NE, et al. Risk of testicular cancer in men with abnormal semen characteristics: cohort study. BMJ 2000; 3: 789-92. doi: 10.1136/bmj.321.7264.789JacobsenRBostofteEEngholmGHansenJOlsenJHSkakkebaekNEet alRisk of testicular cancer in men with abnormal semen characteristics: cohort studyBMJ200037899210.1136/bmj.321.7264.789Open DOISearch in Google Scholar

Raman JD, Nobert CF, Goldstein M. Increased incidence of testicular cancer in men presenting with infertility and abnormal semen analysis. J Urol 2005; 174: 1819-22. doi: 10.1097/01.ju.0000177491.98461.aaRamanJDNobertCFGoldsteinMIncreased incidence of testicular cancer in men presenting with infertility and abnormal semen analysisJ Urol200517418192210.1097/01.ju.0000177491.98461.aaOpen DOISearch in Google Scholar

Sharma RK, Agarwal A. Role of reactive oxygen species in male infertility. Urology 1996; 48: 835-50. doi: 10.1016/s0090-4295(96)00313-5SharmaRKAgarwalARole of reactive oxygen species in male infertilityUrology1996488355010.1016/s0090-4295(96)00313-5Open DOISearch in Google Scholar

Smith R, Vantman D, Ponce J, Escobar J, Lissi E. Total antioxidant capacity of human seminal plasma. Hum Reprod 1996; 11: 1655-60. doi: 10.1093/oxfordjournals.humrep.a019465SmithRVantmanDPonceJEscobarJLissiETotal antioxidant capacity of human seminal plasmaHum Reprod19961116556010.1093/oxfordjournals.humrep.a0194658921112Open DOISearch in Google Scholar

Pahune PP, Choudhari AR, Muley PA. The total antioxidant power of semen and its correlation with the fertility potential of human male subjects. J Clin Diagn Res 2013; 7: 991-5. doi: 10.7860/JCDR/2013/4974.3040PahunePPChoudhariARMuleyPAThe total antioxidant power of semen and its correlation with the fertility potential of human male subjectsJ Clin Diagn Res20137991510.7860/JCDR/2013/4974.3040370825723905087Open DOISearch in Google Scholar

Sposito C, Camargo M, Tibaldi DS, Barradas V, Cedenho AP, Nichi M, et al. Antioxidant enzyme profile and lipid peroxidation products in semen samples of testicular germ cell tumor patients submitted to orchiectomy. Int Braz J Urol 2017; 43: 644-51. doi: 10.1590/S1677-5538SpositoCCamargoMTibaldiDSBarradasVCedenhoAPNichiMet alAntioxidant enzyme profile and lipid peroxidation products in semen samples of testicular germ cell tumor patients submitted to orchiectomyInt Braz J Urol2017436445110.1590/S1677-5538Open DOISearch in Google Scholar

World Health Organization. WHO Laboratory manual for the examination and processing of human semen 5th edition. Geneva: WHO Press; 2010.World Health OrganizationWHO Laboratory manual for the examination and processing of human semen 5th editionGenevaWHO Press;201010.1038/aja.2008.57373968420111082Search in Google Scholar

Shamsi MB, Imam SN, Dada R. Sperm DNA integrity assays: diagnostic and prognostic challenges and implications in management of infertility. J Assist Reprod Genet 2011; 28: 1073-85. doi: 10.1007/s10815-011-9631-8ShamsiMBImamSNDadaRSperm DNA integrity assays: diagnostic and prognostic challenges and implications in management of infertilityJ Assist Reprod Genet20112810738510.1007/s10815-011-9631-8322417021904910Open DOISearch in Google Scholar

Hammadeh ME, Al-Hasani S, Rosenbaum P, Schmidt W, Fischer Hammadeh C. Reactive oxygen species, total antioxidant concentration of seminal plasma and their effect on sperm parameters and outcome of IVF/ICSI patients. Arch Gynecol Obstet 2008; 277: 515-26. doi: 10.1007/s00404-007-0507-1HammadehMEAl-HasaniSRosenbaumPSchmidtWFischerHammadeh CReactive oxygen species, total antioxidant concentration of seminal plasma and their effect on sperm parameters and outcome of IVF/ICSI patientsArch Gynecol Obstet20082775152610.1007/s00404-007-0507-118026972Open DOISearch in Google Scholar

Santi D, Spaggiari G, Simoni M. Sperm DNA fragmentation index as a promising predictive tool for male infertility diagnosis and treatment management – meta-analyses. Reprod Biomed Online 2018; 37: 315-26. doi: 10.1016/j.rbmo.2018.06.023SantiDSpaggiariGSimoniMSperm DNA fragmentation index as a promising predictive tool for male infertility diagnosis and treatment management – meta-analysesReprod Biomed Online2018373152610.1016/j.rbmo.2018.06.02330314886Open DOISearch in Google Scholar

Gandini L, Lombardo F, Paoli D, Caponecchia L, Familiari G, Verlengia C, et al. Study of apoptotic DNA fragmentation in human spermatozoa. Hum Reprod 2000; 15: 830-9. doi: 10.1093/humrep/15.4.830GandiniLLombardoFPaoliDCaponecchiaLFamiliariGVerlengiaCet alStudy of apoptotic DNA fragmentation in human spermatozoaHum Reprod200015830910.1093/humrep/15.4.83010739828Open DOISearch in Google Scholar

Piomboni P, Focarelli R, Stendardi A, Ferramosca A, Zara V. The role of mitochondria in energy production for human sperm motility Int J Andro 2012; 35: 109-24. doi: 10.1111/j.1365-2605.2011.01218.xPiomboniPFocarelliRStendardiAFerramoscaAZaraVThe role of mitochondria in energy production for human sperm motilityInt J Andro2012351092410.1111/j.1365-2605.2011.01218.x21950496Open DOISearch in Google Scholar

Marchetti P, Ballot C, Jouy N, Thomas P, Marchetti C. Influence of mitochondrial membrane potential of spermatozoa on in vitro fertilization outcome. Andrologia 2012; 44: 136-41. doi: 10.1111/j.1439-0272.2010.01117.xMarchettiPBallotCJouyNThomasPMarchettiCInfluence of mitochondrial membrane potential of spermatozoa on in vitro fertilization outcomeAndrologia2012441364110.1111/j.1439-0272.2010.01117.x21714802Open DOISearch in Google Scholar

Malić Vončina S, Golob B, Ihan A, Kopitar AN, Kolbezen M, Zorn B. Sperm DNA fragmentation and mitochondrial membrane potential combined are better for predicting natural conception than standard sperm parameters. Fertil Steril 2016; 105: 637-44. doi: 10.1016/j.fertnstert.2015.11.037MalićVončina SGolobBIhanAKopitarANKolbezenMZornBSperm DNA fragmentation and mitochondrial membrane potential combined are better for predicting natural conception than standard sperm parametersFertil Steril20161056374410.1016/j.fertnstert.2015.11.03726696300Open DOISearch in Google Scholar

Imamovic Kumalic S, Pinter B. Review of clinical trials on effects of oral antioxidants on basic semen and other parameters in idiopathic oligoasthenoteratozoospermia. Biomed Res Int 2014; 2014: 426951. doi: 10.1155/2014/426951ImamovicKumalic SPinterBReview of clinical trials on effects of oral antioxidants on basic semen and other parameters in idiopathic oligoasthenoteratozoospermiaBiomed Res Int2014201442695110.1155/2014/426951398893624800224Open DOISearch in Google Scholar

Piomboni P, Gambera L, Serafini F, Campanella G, Morgante G, De Leo V. Sperm quality improvement after natural anti-oxidant treatment of asthenoteratospermic men with leukocytospermia. Asian J Androl 2008; 10: 201-6. doi: 10.1111/j.1745-7262.2008.00356.xPiomboniPGamberaLSerafiniFCampanellaGMorganteGDeLeo VSperm quality improvement after natural anti-oxidant treatment of asthenoteratospermic men with leukocytospermiaAsian J Androl200810201610.1111/j.1745-7262.2008.00356.x18097513Open DOISearch in Google Scholar

Safarinejad MR. Effect of pentoxifylline on semen parameters, reproductive hormones, and seminal plasma antioxidant capacity in men with idiopathic infertility: a randomized double-blind placebo-controlled study. Int Urol Nephrol 2011; 43: 315-28. doi: 10.1007/s11255-010-9826-4SafarinejadMREffect of pentoxifylline on semen parameters, reproductive hormones, and seminal plasma antioxidant capacity in men with idiopathic infertility: a randomized double-blind placebo-controlled studyInt Urol Nephrol2011433152810.1007/s11255-010-9826-420820916Open DOISearch in Google Scholar

Safarinejad MR, Safarinejad S, Shafiei N, Safarinejad S. Effects of the reduced form of coenzyme Q10 (ubiquinol) on semen parameters in men with idiopathic infertility: a double-blind, placebo controlled, randomized study. J Urol 2012; 188: 526-31. doi: 10.1016/j.juro.2012.03.131SafarinejadMRSafarinejadSShafieiNSafarinejadSEffects of the reduced form of coenzyme Q10 (ubiquinol) on semen parameters in men with idiopathic infertility: a double-blind, placebo controlled, randomized studyJ Urol20121885263110.1016/j.juro.2012.03.13122704112Open DOISearch in Google Scholar

Alizadeh F, Javadi M, Karami AA, Gholaminejad F, Kavianpour M, Haghighian HK. Curcumin nanomicelle improves semen parameters, oxidative stress, inflammatory biomarkers, and reproductive hormones in infertile men: a randomized clinical trial. Phytother Res 2018; 32: 514-21. doi: 10.1002/ptr.5998AlizadehFJavadiMKaramiAAGholaminejadFKavianpourMHaghighianHKCurcumin nanomicelle improves semen parameters, oxidative stress, inflammatory biomarkers, and reproductive hormones in infertile men: a randomized clinical trialPhytother Res2018325142110.1002/ptr.599829193350Open DOISearch in Google Scholar

Banihani SA. Effect of ginger (Zingiber officinale) on semen quality. Andrologia 2019; 51: e13296. doi: 10.1111/and.13296BanihaniSAEffect of ginger (Zingiber officinale) on semen qualityAndrologia201951e1329610.1111/and.1329631012134Open DOISearch in Google Scholar

Jannatifar R, Parivar K, Roodbari NH, Nasr-Esfahani MH. Effects of N-acetylcysteine supplementation on sperm quality, chromatin integrity and level of oxidative stress in infertile men. Reprod Biol Endocrinol 2019; 17: 24. doi: 10.1186/s12958-019-0468-9JannatifarRParivarKRoodbariNHNasr-EsfahaniMHEffects of N-acetylcysteine supplementation on sperm quality, chromatin integrity and level of oxidative stress in infertile menReprod Biol Endocrinol2019172410.1186/s12958-019-0468-9637793830771790Open DOISearch in Google Scholar

Lipovac M, Bodner F, Imhof M, Chedraui P. Comparison of the effect of a combination of eight micronutrients versus a standard mono preparation on sperm parameters. Reprod Biol Endocrinol 2016; 4: 84. doi: 10.1186/s12958-016-0219-0LipovacMBodnerFImhofMChedrauiPComparison of the effect of a combination of eight micronutrients versus a standard mono preparation on sperm parametersReprod Biol Endocrinol201648410.1186/s12958-016-0219-0514887027938385Open DOISearch in Google Scholar

Tremellen K, Miari G, Froiland D, Thompson J. A randomized control trial examining the effect of an antioxidant (Menevit) on pregnancy outcome during IVF-ICSI treatment. Aust NZ J Obstet Gynaecol 2007; 47: 216-1. doi: 10.1111/j.1479-828X.2007.00723.xTremellenKMiariGFroilandDThompsonJA randomized control trial examining the effect of an antioxidant (Menevit) on pregnancy outcome during IVF-ICSI treatmentAust NZ J Obstet Gynaecol200747216110.1111/j.1479-828X.2007.00723.x17550489Open DOISearch in Google Scholar

Ghanem H, Shaeer O, El-Segini A. Combination clomiphene citrate and antioxidant therapy for idiopathic male infertility: a randomized controlled trial. Fertil Steril 2010; 93: 2232-5. doi: 10.1016/j.fertnstert.2009.01.117GhanemHShaeerOEl-SeginiACombination clomiphene citrate and antioxidant therapy for idiopathic male infertility: a randomized controlled trialFertil Steril2010932232510.1016/j.fertnstert.2009.01.11719268928Open DOISearch in Google Scholar

Raigani M, Yaghmaei B, Amirjannti N, Lakpour N, Akhondi MM, Zeraati H, et al. The micronutrient supplements, zinc sulphate and folic acid, did not ameliorate sperm functional parameters in oligoasthenoteratozoospermic men. Andrologia 2014; 46: 956-62. doi: 10.1111/and.12180RaiganiMYaghmaeiBAmirjanntiNLakpourNAkhondiMMZeraatiHet alThe micronutrient supplements, zinc sulphate and folic acid, did not ameliorate sperm functional parameters in oligoasthenoteratozoospermic menAndrologia2014469566210.1111/and.1218024147895Open DOISearch in Google Scholar

Yamamoto Y, Aizawa K, Mieno M, Karamatsu M, Hirano Y, Furui K, et al. The effects of tomato juice on male infertility. Asia Pac J Clin Nutr 2017; 26: 6571. doi: 10.6133/apjcn.102015.17YamamotoYAizawaKMienoMKaramatsuMHiranoYFuruiKet alThe effects of tomato juice on male infertilityAsia Pac J Clin Nutr201726657110.6133/apjcn.102015.1728049263Open DOISearch in Google Scholar

Busetto GM, Agarwal A, Virmani A, Antonini G, Ragonesi G, Del Giudice F, et al. Effect of metabolic and antioxidant supplementation on sperm parameters in oligo-astheno-teratozoospermia, with and without varicocele: a double-blind placebo-controlled study. Andrologia 2018; 50: e12927. doi: 10.1111/and.12927BusettoGMAgarwalAVirmaniAAntoniniGRagonesiGDelGiudice Fet alEffect of metabolic and antioxidant supplementation on sperm parameters in oligo-astheno-teratozoospermia, with and without varicocele: a double-blind placebo-controlled studyAndrologia201850e1292710.1111/and.1292729315686Open DOISearch in Google Scholar

Smits RM, Mackenzie-Proctor R, Yazdani A, Stankiewicz MT, Jordan V, Showell MG. Antioxidants for male subfertility. Cochrane Database Syst Rev 2019; 3: CD007411. doi: 10.1002/14651858.CD007411.pub4SmitsRMMackenzie-ProctorRYazdaniAStankiewiczMTJordanVShowellMGAntioxidants for male subfertilityCochrane Database Syst Rev20193CD00741110.1002/14651858.CD007411.pub4Open DOISearch in Google Scholar

Yuan JP, Peng J, Yin K, Wang JH. Potential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgae. Mol Nutr Food Res 2011; 55: 150-65. doi: 10.1002/mnfr.201000414YuanJPPengJYinKWangJHPotential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgaeMol Nutr Food Res2011551506510.1002/mnfr.201000414Open DOISearch in Google Scholar

Miki W. Biological functions and activities of animal carotenoids. Pure Appl Chem 1991; 63: 141-6. doi: 10.1351/pac199163010141MikiWBiological functions and activities of animal carotenoidsPure Appl Chem199163141610.1351/pac199163010141Open DOISearch in Google Scholar

Dona G, Kozuh I, Brunati AM, Andrisani A, Ambrosini G, Bonanni G, et al. Effect of astaxanthin on human sperm capacitation. Mar Drugs 2013; 11: 1909-19. doi: 10.3390/md11061909DonaGKozuhIBrunatiAMAndrisaniAAmbrosiniGBonanniGet alEffect of astaxanthin on human sperm capacitationMar Drugs20131119091910.3390/md11061909Open DOISearch in Google Scholar

Andrisani A, Donà G, Tibaldi E, Brunati AM, Sabbadin C, Armanini D, et al. Astaxanthin improves human sperm capacitation by inducing lyn displacement and activation. Mar Drugs 2015; 13: 5533-51. doi: 10.3390/ md13095533AndrisaniADonàGTibaldiEBrunatiAMSabbadinCArmaniniDet alAstaxanthin improves human sperm capacitation by inducing lyn displacement and activationMar Drugs20151355335110.3390/md13095533Open DOISearch in Google Scholar

Comhaire FH, El Garem Y, Mahmoud A, Eertmans F, Schoonjans F. Combined conventional/antioxidant “Astaxanthin” treatment for male infertility: a double blind, randomized trial. Asian J Androl 2005; 7: 257-62. doi: 10.1111/j.1745-7262.2005.00047.xComhaireFHElGarem YMahmoudAEertmansFSchoonjansFCombined conventional/antioxidant “Astaxanthin” treatment for male infertility: a double blind, randomized trialAsian J Androl200572576210.1111/j.1745-7262.2005.00047.xOpen DOISearch in Google Scholar

Björndahl L, Barratt CLR, Mortimer D, Jouannet P. ‘How to count sperm properly’: checklist for acceptability of studies based on human semen analysis. Hum Reprod 2016; 31: 227-32. doi: 10.1093/humrep/dev305BjörndahlLBarrattCLRMortimerDJouannetP.‘How to count sperm properly’: checklist for acceptability of studies based on human semen analysisHum Reprod2016312273210.1093/humrep/dev305Open DOISearch in Google Scholar

Franco JG Jr, Baruffi RL, Mauri AL, Petersen CG, Oliveira JB, Vagnini L. Significance of large nuclear vacuoles in human spermatozoa: implications for ICSI. Reprod Biomed Online 2008; 17: 42-5. doi: 10.1016/s1472-6483(10)60291-xFrancoJGJrBaruffiRLMauriALPetersenCGOliveiraJBVagniniLSignificance of large nuclear vacuoles in human spermatozoa: implications for ICSIReprod Biomed Online20081742510.1016/s1472-6483(10)60291-xOpen DOISearch in Google Scholar

Sergerie M, Laforest G, Bujan L, Bissonnette F, Bleau G. Sperm DNA fragmentation: threshold value in male fertility. Hum Reprod 2005; 20: 3446-51. doi: 10.1093/humrep/dei231SergerieMLaforestGBujanLBissonnetteFBleauGSperm DNA fragmentation: threshold value in male fertilityHum Reprod20052034465110.1093/humrep/dei231Open DOISearch in Google Scholar

Armstrong JS, Rajasekaran M, Chamulitrat W, Gatti P, Hellstrom WJ, Sikka SC. Characterization of reactive oxygen species induced effects on human spermatozoa movement and energy metabolism. Free Radic Biol Med 1999; 26: 869-80. doi: 10.1016/s0891-5849(98)00275-5ArmstrongJSRajasekaranMChamulitratWGattiPHellstromWJSikkaSCCharacterization of reactive oxygen species induced effects on human spermatozoa movement and energy metabolismFree Radic Biol Med1999268698010.1016/s0891-5849(98)00275-5Open DOISearch in Google Scholar

Colpi GM, Contalbi GF, Nerva F, Sagone P, Piediferro G. Testicular function following chemo-radiotherapy. Eur J Obstet Gynecol Reprod Biol 2004; 13(Suppl 1): S2-6. doi: 10.1016/j.ejogrb.2003.11.002ColpiGMContalbiGFNervaFSagonePPiediferroGTesticular function following chemo-radiotherapyEur J Obstet Gynecol Reprod Biol200413Suppl1S2610.1016/j.ejogrb.2003.11.002Open DOISearch in Google Scholar

Pont J, Albrecht W. Fertility after chemotherapy for testicular germ cell cancer. Fertil Steril 1997; 68: 1-5. doi: 10.1016/s0015-0282(97)81465-3PontJAlbrechtWFertility after chemotherapy for testicular germ cell cancerFertil Steril1997681510.1016/s0015-0282(97)81465-3Open DOISearch in Google Scholar

Fossa SD, Aass N, Molne K. Is routine pre-treatment cryopreservation of semen worthwhile in the management of patients with testicular cancer? Br J Urol 1989; 64: 524-9. doi: 10.1111/j.1464-410x.1989.tb05292.xFossaSDAassNMolneKIs routine pre-treatment cryopreservation of semen worthwhile in the management of patients with testicular cancer?Br J Urol198964524910.1111/j.1464-410x.1989.tb05292.xOpen DOISearch in Google Scholar

Horwich A, Nicholls EJ, Hendry WF. Seminal analysis after orchiectomy in stage I teratoma. Br J Urol 1988; 62: 79-81. doi: 10.1111/j.1464-410x.1988.tb04272.xHorwichANichollsEJHendryWFSeminal analysis after orchiectomy in stage I teratomaBr J Urol198862798110.1111/j.1464-410x.1988.tb04272.xOpen DOISearch in Google Scholar

Berthelsen JG. Sperm counts and serum follicle-stimulating hormone levels before and after radiotherapy and chemotherapy in men with testicular germ cell cancer. Fertil Steril 1984; 41: 281-6. doi: 10.1016/s0015-0282(16)47605-3BerthelsenJGSperm counts and serum follicle-stimulating hormone levels before and after radiotherapy and chemotherapy in men with testicular germ cell cancerFertil Steril198441281610.1016/s0015-0282(16)47605-3Open DOISearch in Google Scholar

Rueffer U, Breuer K, Josting A, Lathan B, Sieber M, Manzke O, et al. Male gonadal dysfunction in patients with Hodgkin’s disease prior to treatment. Ann Oncol 2001; 12: 1307-11. doi: 10.1023/a:1012464703805RuefferUBreuerKJostingALathanBSieberMManzkeOet alMale gonadal dysfunction in patients with Hodgkin’s disease prior to treatmentAnn Oncol20011213071110.1023/a:1012464703805Open DOISearch in Google Scholar

Van der Kaaij MA, Heutte N, Echten AJV, Raemaekers JMM, Carde P, Noordijk EM, et al. Sperm quality before treatment in patients with early stage Hodgkin’s lymphoma enrolled in EORTC-GELA lymphoma group trials. Haematologica 2009; 94: 1691-7. doi: 10.3324/haematol.2009.009696Vander Kaaij MAHeutteNEchtenAJVRaemaekersJMMCardePNoordijkEMet alSperm quality before treatment in patients with early stage Hodgkin’s lymphoma enrolled in EORTC-GELA lymphoma group trialsHaematologica2009941691710.3324/haematol.2009.009696Open DOISearch in Google Scholar

Viviani S, Ragni G, Santoro A, Perotti L, Caccamo E, Negretti E, et al. Testicular dysfunction in Hodgkin’s disease before and after treatment. Eur J Cancer 1991; 27: 1389-92. doi: 10.1016/0277-5379(91)90017-8VivianiSRagniGSantoroAPerottiLCaccamoENegrettiEet alTesticular dysfunction in Hodgkin’s disease before and after treatmentEur J Cancer19912713899210.1016/0277-5379(91)90017-8Open DOISearch in Google Scholar

Steiner A, Hansen K, Diamond MP, Coutifaris C, Cedars M, Legro R, et al. Antioxidants in the treatment of male factor infertility: results from double blind, multi-center, randomized controlled males, antioxidants, and infertility (MOXI) trial. [abstract O-064]. In: Abstracts of the 34th annual meeting of the European Society of Human Reproduction and Embryology 2018. Hum Reprod 33(Supp 1): i30.SteinerAHansenKDiamondMPCoutifarisCCedarsMLegroRet alAntioxidants in the treatment of male factor infertility: results from double blind, multi-center, randomized controlled males, antioxidants, and infertility (MOXI) trial. [abstract O-064]InAbstracts of the 34th annual meeting of the European Society of Human Reproduction and Embryology2018 Hum Reprod33Supp1i30Search in Google Scholar

Donnelly ET, McClure N, Lewis SE. Antioxidant supplementation in vitro does not improve human sperm motility. Fertil Steril 1999; 72: 484-95. doi: 10.1016/s0015-0282(99)00267-8DonnellyETMcClureNLewisSEAntioxidant supplementation in vitro does not improve human sperm motilityFertil Steril1999724849510.1016/s0015-0282(99)00267-8Open DOISearch in Google Scholar

Safarinejad MR, Shafiei N, Safarinejad S. A prospective double-blind randomized placebo-controlled study of the effect of saffron (Crocussativus Linn.) on semen parameters and seminal plasma antioxidant capacity in infertile men with idiopathic oligoasthenoteratozoospermia. Phytother Res 2011; 25: 508-16. doi: 10.1002/ptr.3294SafarinejadMRShafieiNSafarinejadSA prospective double-blind randomized placebo-controlled study of the effect of saffron (Crocussativus Linn.) on semen parameters and seminal plasma antioxidant capacity in infertile men with idiopathic oligoasthenoteratozoospermiaPhytother Res2011255081610.1002/ptr.329420824894Open DOISearch in Google Scholar

Rafiee B, Morowvat MH, Rahimi-Ghalati N. Comparing the effectiveness of dietary vitamin C and exercise interventions on fertility parameters in normal obese men. Urol J 2016; 13: 2635-9. PMID: 27085565RafieeBMorowvatMHRahimi-GhalatiNComparing the effectiveness of dietary vitamin C and exercise interventions on fertility parameters in normal obese menUrol J20161326359PMID: 27085565Search in Google Scholar

Bozhedomov VA, Lipatova NA, Bozhedomova GE, Rokhlikov IM, Shcherbakova EV, Komarina RA. Using L- and acetyl-L-carnintines in combination with clomiphene citrate and antioxidant complex for treating idiopathic male infertility: a prospecitive randomized trial. Urologia 2017; 3: 22-32. doi: 10.18565/urol.2017.3.22-32BozhedomovVALipatovaNABozhedomovaGERokhlikovIMShcherbakovaEVKomarinaRAUsing L- and acetyl-L-carnintines in combination with clomiphene citrate and antioxidant complex for treating idiopathic male infertility: a prospecitive randomized trialUrologia20173223210.18565/urol.2017.3.22-3228845935Open DOISearch in Google Scholar

Kirsch I. How expectancies shape experience Washington: American Psychological Association; 1999.KirschIHow expectancies shape experienceWashingtonAmerican Psychological Association;199910.1037/10332-000Search in Google Scholar

Bjørkedal E, Flaten MA. Interaction between expectancies and drug effects: an experimental investigation of placebo analgesia with caffeine as an active placebo. Psychopharmacology 2011; 215: 537-48. doi: 10.1007/s00213-011-2233-4BjørkedalEFlatenMAInteraction between expectancies and drug effects: an experimental investigation of placebo analgesia with caffeine as an active placeboPsychopharmacology20112155374810.1007/s00213-011-2233-4309057621384106Open DOISearch in Google Scholar

Benedetti F. Placebo-effects: understanding the mechanisms in health and disease Oxford: Oxford University Press; 2009.BenedettiFPlacebo-effects: understanding the mechanisms in health and diseaseOxfordOxford University Press;2009Search in Google Scholar

Ahmadi S, Bashiri R, Ghadiri-Anari A, Nadjarzadeh A. Antioxidant supplements and semen parameters: an evidence based review. Int J Reprod Biomed 2016; 14: 729-36. PMID: 28066832AhmadiSBashiriRGhadiri-AnariANadjarzadehAAntioxidant supplements and semen parameters: an evidence based reviewInt J Reprod Biomed20161472936PMID: 2806683210.29252/ijrm.14.12.729Search in Google Scholar

Bergmann M, Behre HM, Nieschlag E. Serum FSH and testicular morphology in male infertility. Clin Endocrinol 1994; 40: 133-6. doi: 10.1111/j.1365-2265.1994.tb02455.xBergmannMBehreHMNieschlagESerum FSH and testicular morphology in male infertilityClin Endocrinol199440133610.1111/j.1365-2265.1994.tb02455.x8306472Open DOISearch in Google Scholar

Kumar R, Saxena V, Shamsi MB, Venkatesh S, Dada R. Herbo-mineral supplementation in men with idiopathic oligoasthenoteratospermia: a double blind randomized placebo- controlled trial. Indian J Urol 2011; 27: 357-62. doi: 10.4103/0970-1591.85440KumarRSaxenaVShamsiMBVenkateshSDadaRHerbo-mineral supplementation in men with idiopathic oligoasthenoteratospermia: a double blind randomized placebo- controlled trialIndian J Urol2011273576210.4103/0970-1591.85440319373622022059Open DOISearch in Google Scholar

Nadjarzadeh A, Shidfar F, Amirjannati N, Vafa MR, Motevalian SA, Gohari MR, et al. Effect of coenzyme Q10 supplementation on antioxidant enzymes activity and oxidative stress of seminal plasma: a double-blind randomised clinical trial. Andrologia 2014; 46: 177-83. doi: 10.1111/and.12062NadjarzadehAShidfarFAmirjannatiNVafaMRMotevalianSAGohariMRet alEffect of coenzyme Q10 supplementation on antioxidant enzymes activity and oxidative stress of seminal plasma: a double-blind randomised clinical trialAndrologia2014461778310.1111/and.1206223289958Open DOISearch in Google Scholar

Sandercock P. Negative results: why do they need to be published? Int J Stroke 2012; 7: 32-33. doi: 10.1111/j.1747-4949.2011.00723.xSandercockPNegative results: why do they need to be published?Int J Stroke20127323310.1111/j.1747-4949.2011.00723.x22188851Open DOISearch in Google Scholar

Mlinarić A, Horvat M, Šupak Smolčić V. Dealing with the positive publication bias: why you should really publish your negative results. Biochem Med 2017; 27: 030201. doi: 10.11613/BM.2017.030201MlinarićAHorvatMŠupakSmolčić VDealing with the positive publication bias: why you should really publish your negative resultsBiochem Med20172703020110.11613/BM.2017.030201569675129180912Open DOISearch in Google Scholar

Hart B, Duke D, Lundh A, Bero L. Effect of reporting bias on meta-analyses of drug trials: reanalysis of meta-analyses. BMJ 2012; 344: d7202. doi: 10.1136/bmj.d7202HartBDukeDLundhABeroLEffect of reporting bias on meta-analyses of drug trials: reanalysis of meta-analysesBMJ2012344d720210.1136/bmj.d720222214754Open DOISearch in Google Scholar

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