<abstract xmlns="http://www.w3.org/1999/xhtml">

The aim of the present study was to assess the suitability of different Amicon Ultra and Centrifree ultrafiltration devices for the study of the plasma protein binding process in the case of carvedilol, a highly protein-bound and lipophilic beta-blocking agent. Samples at different levels of concentration were prepared in both proteic and non-proteic matrices (human plasma, 5% human serum albumin solution and saline solution) and subjected to the classical ultrafiltration method using the different devices considered. Furthermore, an attempt to apply a previously described modified ultrafiltration method was also made. The analysis and quantification was achieved using a validated LC-MS/MS method. For the Centrifree devices, the determined unbound fractions of carvedilol and the corresponding binding degree were in accordance to literature data, while for the Amicon Ultra devices a great degree of carvedilol adsorbtion to the sample reservoir was observed, the analyte not being detected in the ultrafiltrate samples. Thus, it was further demonstrated that the type of ultrafiltration device used has a significant influence on the outcome of a plasma protein binding study. In the case of carvedilol, the evaluation of the protein binding interaction could be achieved using the Centrifree ultrafiltration devices, but not the Amicon Ultra devices.
</abstract>

I.O.S.U.D., George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures

Department of Analytical Chemistry and Drug Analysis, Faculty of Pharmacy

George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures

Comparison of Different Ultrafiltration Devices for the Study of Plasma Protein Binding of Carvedilol

<abstract xmlns="http://www.w3.org/1999/xhtml">

Dietary supplements can provide the necessary nutrients for groups of people who need them, but their use comes with a few risks, such as excessive or unwarranted utilization, side effects, unwanted interactions, and the promotion of unhealthy behaviors or neglecting professional health care. This cross-sectional study analyzed 49 TV advertisements on three major news channels in Romania regarding their compliance with European and national laws concerning the advertisement of dietary supplements. A list of criteria was extracted from the current laws in Romania and was used to check the video promotional materials’ compliance systematically. Despite more than half of the commercials complying with the technical criteria, it was found that a concerning amount of advertisements targeted people with various or specific pathologies, while a third of the ads included non-compliant words or representations associated with pathologies and medical professionals or institutions. As a practical implication, the study suggests a need for more consistent and closer surveillance of dietary supplement commercials broadcasted in the Romanian media.
</abstract>

George Emil Palade University of Medicine, Pharmacy

Unveiling Deceptive Claims: A Cross-Sectional Observational Assessment of Dietary Supplement Advertisements from Three News Channels in Romania

<abstract xmlns="http://www.w3.org/1999/xhtml">

The aim of this paper is to point out plant species that are of benefit to pollinators, from the territory of the Băiceni (Botoșani county, NE region of Romania). The plant species were analyzed on the basis of the specialized literature as follows: bioform, flowering period, flower grouping, flower color, floral resources, melliferous potential. A number of 106 plant species belonging to 31 botanical families were identified; 41.50% are woody species and 58.50% are herbaceous species. The representative botanical families are: Rosaceae (19.81%), Fabaceae (14.15%) and Asteraceae (14.15%). The majority of the species recorded in the area of study have flowers grouped in inflorescences, blooming in spring and summer and are nectar-polleniferous. The color of the flowers varies from white, yellow, yellow-green to red, blue, purple. These species are an essential resource for pollinators (mainly for the honeybee) and thus contribute to keeping the ecological equilibrium of the ecosystems in the study area and to supporting local beekeeping.
</abstract>

Departament of Biology, Faculty of Biology

“Alexandru Ioan Cuza” University of Iasi

Plant Species Important for Pollinating Insects. Case Study: Băiceni Locality (Botoşani County)

<abstract xmlns="http://www.w3.org/1999/xhtml">

The study of non-historical monument gardens aimed to inventory and assess their current state compared to the original. These gardens were researched in detail, following the steps used for historical parks and gardens. Unclassified gardens were categorized using newly established criteria based on collected information. While there’s less data about these gardens compared to historical ones, the primary goal of redevelopment is to recreate their era’s ambiance while preserving existing landscape, dendrological, and architectural values.
</abstract>

Department of Horticulture, Faculty of Technical and Human Sciences

Sapientia Hungarian University of Transylvania

“Ion Mincu” University of Architecture and Urban Planning Bucharest

Rediscovering the Historical Gardens in the Banat County

<abstract xmlns="http://www.w3.org/1999/xhtml">

Nowadays’ (Transylvanian) urban landscape as a complex, built and natural, social and economic environment is undergoing a sudden and accelarated transformation. Urbanization is a defining feature of current spatial/urban metamorphosis in Transylvania, too, yet the current model of urban development profoundly alters the natural environment, often reducing biodiversity and ultimately threatening human wellbeing. Present not only in academic theory, but in a broader sense in the daily public debate for the past decades, ecological perspective has become one of the leading design principles in nowadays’ professional practice and theory in urban and spatial planning, a compulsory attribute of the contemporary mindset and (urban) landscape. Proposed research on ecological perspective in current urban (landscape) planning in Transylvania, Romania is focusing specifically on the role ecological perspective can play in understanding, the applying the more general and complex phenomenon of sustainability in the planning and management of landscapes. The idea of sustainability, the ecoregional approach are not only traditional attributes of the historical landscape, but also generators in present day development of cities around Transylvania, Romania. The ecological approach can enhance finding solutions in urgent social and environmental challanges regarding efficient management of resources, sustainable urban and spatial planning.
</abstract>

The Ecological Perspective in Nowadays’ Urban Landscape Planning in Transylvania

<abstract xmlns="http://www.w3.org/1999/xhtml">

Cyanobacteria are well-distributed, because of their ability to acclimate to various environments. Recently, cyanobacteria have received more research attention due to increasing pollution problems and global warming. They have many potential applications in the biotechnology sectors such as pharmaceuticals, bioplastics production, and cosmetics. Cyanobacteria produce many biologically active compounds that are utilized as anti-inflammatory, antiviral, antibacterial, and antifungal agents. The bioactive metabolites extracted from cyanobacteria include alkaloids, fatty acids, lipopeptides, and amides. In this minireview, the potential of some biotechnical applications are summarized to provide an account of the recent advancements in cyanobacteria research.
</abstract>

Department of Marine Biology, Faculty of Marine Sciences

Department of Marine Biology and Fisheries, Faculty of Marine Sciences and Environments

Department of Biology, Faculty of Sciences

A Mini Review on Biotechnological Potentials of Bioactive Compounds and Bioproducts Isolated from Cyanobacteria

<abstract xmlns="http://www.w3.org/1999/xhtml">

This short overview explores the relationship between oxidative stress and mental disorders, focusing on the association with psychiatric pathologies such as Alzheimer’s disease, schizophrenia, autism, depression, and the impact of sleep deprivation. The mechanisms of mitochondrial disfunction and oxidative stress in these pathologies are described, including the physiological function of limited free radicals in signal transduction, gene transcription, neuronal plasticity and memory. Key free radicals, including hydroxyl and superoxide are highlighted, along with compounds generating free radicals. Moreover, the potential therapeutic implications of dietary supplements (zinc, selenium, magnesium, vitamin C, E, CoQ10) and lifestyle interventions with antioxidant properties are presented, laying the groundwork for future research in the field of mental health.
</abstract>

George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș

Short Overview of Oxidative Stress in Mental Disorders

<abstract xmlns="http://www.w3.org/1999/xhtml">

The Giurgeului Depression has been significantly impacted by human intervention, resulting in numerous scars on the landscape. A comprehensive rehabilitation plan is imperative for the Suseni quarry area to restore its natural features. This initiative, spearheaded by the local council and municipality, collaborates with the Sapientia Hungarian University of Transylvania’s Department of Horticulture and the Babeș-Bolyai University’s Faculty of Biology and Geology. They’ve launched a research scholarship program for students focused on a research and landscape rehabilitation plan tender within Suseni’s administrative region. Large scars created by human activities, adjacent to a valuable natural environment, significantly alter the natural landscape features and are detrimental to the visual and ecological relationship systems. Those need urgent rehabilitation. Student projects serves as a potential model for transforming natural landscapes affected by human actions. It aims to teach landscape design through experimental approaches, aligning with modern research-driven design methods for strategic planning. Moreover, it seeks to enhance student projects for practical implementation by local authorities, contributing positively to the area’s ecosystem and landscape. Much has already been taken from this landscape, and it is now time to give something back to the area, the local ecosystem, and the landscape.
</abstract>

The Role of a Landscape Rehabilitation Student Project in Current Landscape Education - Healing Urbanization’s Footprint

<abstract xmlns="http://www.w3.org/1999/xhtml">

Liverworts and mosses are terrestrial plants that contain biologically active substances that give them important medicinal qualities. After reviewing the available literature on the pharmacological activity of the most used liverworts and mosses, we present 34 species found in Romania, used for the treatment of common diseases in folk medicine around the world. Their uses in traditional medicine are sometimes confirmed by pharmacological research, especially external ones (as antimicrobial or cytotoxic remedies). The species of liverworts and mosses are mentioned with their distribution in Romanian flora and the habitats where they live.
</abstract>

Liverworts and Mosses from Romania with Medicinal Potential

AHEAD OF PRINT

Volume 6 (2023): Issue 2 (December 2023)

Volume 6 (2023): Issue 1 (June 2023)

Volume 5 (2022): Issue 2 (December 2022)

Volume 5 (2022): Issue 1 (June 2022)

Volume 4 (2021): Issue 2 (December 2021)

Volume 4 (2021): Issue 1 (June 2021)

Volume 3 (2020): Issue 2 (December 2020)

Volume 3 (2020): Issue 1 (June 2020)

Volume 2 (2019): Issue 2 (December 2019)

Volume 2 (2019): Issue 1 (June 2019)

Volume 1 (2018): Issue 2 (December 2018)

Volume 1 (2018): Issue 1 (June 2018)

Acta Biologica Marisiensis

 Acta Biologica Marisiensis (ABM) is an official Journal of the University of Medicine, Pharmacy, Science and Technology “George Emil Palade” of Târgu Mureș, Romania, and is published twice a year. The peer-reviewed journal is dedicated to the life sciences and publishes articles in the following fields: biochemistry, botany, cell biology and molecular biology, biotechnology, ecology, genetics, microbiology, pharmacognosy, phytochemistry.  Both original research papers and reviews are welcomed. The journal addresses the entire academic community of specialists and researchers activate in different fields of life sciences and pharmacy, and its goal is to provide them the latest research developments in their field of activity.  Acta Biologica Marisiensis is the official publication of the University of Medicine, Pharmacy, Science and Technology “George Emil Palade” of Târgu Mureș, being published by University Press. The journal is published in every year since 1964 under the name Note Botanice. Since 2018 it is published with a new name, Acta Biologica Marisiensis, included as a new series in Acta Marisiensis.  The journal publishes high-quality articles on various subjects dedicated to the life sciences in the following fields: biochemistry, botany, cell biology and molecular biology, biotechnology, ecology, genetics, microbiology, pharmacognosy, phytochemistry.   Why subscribe and read   It is an international peer-reviewed, open access journal published two times per year, only in English language.  The Journal is designed to facilitate the exchange of ideas between researchers from different countries all around the world.  The Journal has high standards for its contents. It has good publishing quality in electronic and printed form.   Why submit   the Journal is always freely available online  fast, fair and constructive peer review procedure  no payment for article processing or publishing fee is required from authors  free publication of color figures, graphs and tables in published articles  immediate publication of articles  worldwide dissemination and unrestricted access to all published articles  high quality publishing, available in both forms, electronic and printed  promotion of each article in numerous abstracting databases   Archiving  Sciendo archives the contents of this journal in Portico - digital long-term preservation service of scholarly books, journals and collections.  Plagiarism Policy  The editorial board is participating in a growing community of Similarity Check System's users in order to ensure that the content published is original and trustworthy. Similarity Check is a medium that allows for comprehensive manuscripts screening, aimed to eliminate plagiarism and provide a high standard and quality peer-review process. 