<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Oat is rich in valuable nutrients. In comparison to other cereals, oat contains more total proteins, carbohydrate, fat, non-starch fibre, as well as unique antioxidants (one of them - avenanthramides), vitamins, and minerals. One of the most often studied components of oats is β-glucan - a type of soluble dietary fibre located throughout the starch endosperm, but with highest concentration in the bran. Many studies have shown the beneficial health effects of oat β-glucan as a soluble dietary fibre. Until now, most of the studies on this nutrient have been conducted in the cardiovascular and diabetology field. This article aimed to review the literature on studies that investigated the effects of oat-based products on human gastrointestinal tract - gastrointestinal microflora, irritable bowel syndrome, inflammatory bowel disease as well as prevention/treatment of colorectal cancer. A literature search was conducted using PubMed database. More than 80 potential articles were identified, which were selected afterwards according to aims of our study. Studies done on human were preferred. A long-term dietary intake of oat-based products improves human intestinal microflora, could have benefits in irritable bowel syndrome, and probable effects were seen in patients with ulcerative colitis, but this remains to be proven. There are few studies regarding prevention/treatment of colorectal cancer and they do not show clear benefit nor provide recommendations. </p></abstract>

Oat is rich in valuable nutrients. In comparison to other cereals, oat contains more total proteins, carbohydrate, fat, non-starch fibre, as well as unique antioxidants (one of them - avenanthramides), vitamins, and minerals. One of the most often studied components of oats is β-glucan - a type of soluble dietary fibre located throughout the starch endosperm, but with highest concentration in the bran. Many studies have shown the beneficial health effects of oat β-glucan as a soluble dietary fibre. Until now, most of the studies on this nutrient have been conducted in the cardiovascular and diabetology field. This article aimed to review the literature on studies that investigated the effects of oat-based products on human gastrointestinal tract - gastrointestinal microflora, irritable bowel syndrome, inflammatory bowel disease as well as prevention/treatment of colorectal cancer. A literature search was conducted using PubMed database. More than 80 potential articles were identified, which were selected afterwards according to aims of our study. Studies done on human were preferred. A long-term dietary intake of oat-based products improves human intestinal microflora, could have benefits in irritable bowel syndrome, and probable effects were seen in patients with ulcerative colitis, but this remains to be proven. There are few studies regarding prevention/treatment of colorectal cancer and they do not show clear benefit nor provide recommendations.

Impact of Oat-Based Products on Human Gastrointestinal Tract

Gastroenterology, Hepatology and Nutrition Centre, Pauls Stradiņš Clinical University Hospital, Pilsoņu iela 13, Rīga, LV-1002, LATVIA

Faculty of Chemistry, University of Latvia, Kr. Valdemāra iela 48, Rīga, LV-1013, LATVIA

Faculty of Medicine, University of Latvia, Raiņa bulv. 19, Rīga, LV-1586, LATVIA

Rīga Stradiņš University, Faculty of Medicine, Dzirciema iela 16, Rīga, LV-1007, LATVIA

Gastroenterology, Hepatology and Nutrition Centre, Pauls Stradiņš Clinical University Hospital, Pilsoņšu iela 13, Rīga, LV-1002, LATVIA

Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Impact of Oat-Based Products on Human Gastrointestinal Tract"}

Oat is rich in valuable nutrients. In comparison to other cereals, oat contains more total proteins, carbohydrate, fat, non-starch fibre, as well as unique...

Impact of Oat-Based Products on Human Gastrointestinal Tract

Published Online: Oct 06, 2015

Page range: 145 - 151

Received: Apr 14, 2015

DOI: https://doi.org/10.1515/prolas-2015-0021

Keywords
Avena sativa, gastrointestinal microflora, irritable bowel syndrome, inflammatory bowel disease, colorectal cancer

© by Aiga Staka

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Impact of Oat-Based Products on Human Gastrointestinal Tract

Published Online: Oct 06, 2015

Page range: 145 - 151

Received: Apr 14, 2015

DOI: https://doi.org/10.1515/prolas-2015-0021

KeywordsAvena sativa, gastrointestinal microflora, irritable bowel syndrome, inflammatory bowel disease, colorectal cancer

© by Aiga Staka

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Avena sativa, gastrointestinal microflora, irritable bowel syndrome, inflammatory bowel disease, colorectal cancer