PRKAA2 variation and the clinical characteristics of patients newly diagnosed with type 2 diabetes mellitus in Yogyakarta, Indonesia
, and | Aug 20, 2021
Article Category: Original article
Published Online: Aug 20, 2021
Page range: 161 - 170
DOI: https://doi.org/10.2478/abm-2021-0021
Keywords
© 2021 Dita Maria Virginia et al., published by Sciendo
This work is licensed under the Creative Commons Attribution 4.0 International License.
Background
Adenosine monophosphate (AMP)-activated protein kinase (AMPK; EC 2.7.11.31) enzymes play a pivotal role in cell metabolism. They are involved in type 2 diabetes mellitus (T2DM) pathogenesis. Genetic variation of
Objectives
To determine the association between
Methods
We performed a cross-sectional study including 166 T2DM patients from 10 primary health care centers in Yogyakarta, Indonesia. We measured fasting plasma glucose, hemoglobin A1c, serum creatinine, glomerular filtration rate, blood pressure, and body mass index as clinical characteristics.
Results
There was no difference in clinical characteristics for genotypes rs2796498, rs9803799, or rs2746342 (