<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>This short overview explores the relationship between oxidative stress and mental disorders, focusing on the association with psychiatric pathologies such as Alzheimer’s disease, schizophrenia, autism, depression, and the impact of sleep deprivation. The mechanisms of mitochondrial disfunction and oxidative stress in these pathologies are described, including the physiological function of limited free radicals in signal transduction, gene transcription, neuronal plasticity and memory. Key free radicals, including hydroxyl and superoxide are highlighted, along with compounds generating free radicals. Moreover, the potential therapeutic implications of dietary supplements (zinc, selenium, magnesium, vitamin C, E, CoQ<sub>10</sub>) and lifestyle interventions with antioxidant properties are presented, laying the groundwork for future research in the field of mental health.</p>
</abstract>

This short overview explores the relationship between oxidative stress and mental disorders, focusing on the association with psychiatric pathologies such as Alzheimer’s disease, schizophrenia, autism, depression, and the impact of sleep deprivation. The mechanisms of mitochondrial disfunction and oxidative stress in these pathologies are described, including the physiological function of limited free radicals in signal transduction, gene transcription, neuronal plasticity and memory. Key free radicals, including hydroxyl and superoxide are highlighted, along with compounds generating free radicals. Moreover, the potential therapeutic implications of dietary supplements (zinc, selenium, magnesium, vitamin C, E, CoQ10) and lifestyle interventions with antioxidant properties are presented, laying the groundwork for future research in the field of mental health.

Short Overview of Oxidative Stress in Mental Disorders

George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureș

Acta Biologica Marisiensis

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"Short Overview of Oxidative Stress in Mental Disorders"}

This short overview explores the relationship between oxidative stress and mental disorders, focusing on the association with psychiatric pathologies such as...

Short Overview of Oxidative Stress in Mental Disorders

Published Online: Dec 22, 2023

Page range: 87 - 99

Received: Nov 22, 2023

Accepted: Dec 15, 2023

DOI: https://doi.org/10.2478/abmj-2023-0013

Keywords
oxidative stress, mental disorder, dietary supplements, antioxidants

© 2023 Julika Runlin Tan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Short Overview of Oxidative Stress in Mental Disorders

Published Online: Dec 22, 2023

Page range: 87 - 99

Received: Nov 22, 2023

Accepted: Dec 15, 2023

DOI: https://doi.org/10.2478/abmj-2023-0013

Keywordsoxidative stress, mental disorder, dietary supplements, antioxidants

© 2023 Julika Runlin Tan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
oxidative stress, mental disorder, dietary supplements, antioxidants