<abstract xmlns="http://www.w3.org/1999/xhtml">

Newcastle disease (ND) is a highly contagious viral disease. This study was conducted to determine the antibody titer in Japanese quails following vaccination against ND and feed-supplementation with vitamin-C, probiotics and antibiotic-growth-promoters. Forty Japanese quails were equally grouped in four groups (A1 to A4) and were vaccinated by LaSota, B1, F and VG/GA strains, respectively, at the age of 10 days. Another forty Japenese quails were equally grouped in four groups (B1 to B4), were vaccinated with the vaccines of the previous groups that showed a higher effect, and were fed with mesh-feed (control-B1), supplemented with vitamin-C (B2), probiotics (B3), and antibiotic growth promoter (B4). Serum samples were obtained on 2, 4, 6, 8, 10 and 12 weeks of age and were subjected to a hemagglutination inhibition test. The mean antibody titer (Log2) had no significant difference between groups A1-A4. The highest titers were recorded in A4 (6.20±0.37) and A3 (6.00±0.71). The mean titer was significantly different among the groups at 4 weeks, but insignificant in the other weeks of the supplemented groups. A higher mean titer was found between 8 and 10 weeks in group B2 (7.40±0.60) and B3 (7.20±0.58). The relative weights (gm/kg) of the spleen, thymus and bursa were significantly higher in group B3 (1.947±0.109, 5.951±0.312 and 2.624±0.083, respectively). They had no significant correlation with antibody titer at 12 weeks. In conclusion, vitamin-C and probiotic supplemented feeds can boost up the antibody titer against ND in Japanese quail when given during VG/GA strain vaccination.
</abstract>

Newcastle disease (ND) is a highly contagious viral disease. This study was conducted to determine the antibody titer in Japanese quails following vaccination against ND and feed-supplementation with vitamin-C, probiotics and antibiotic-growth-promoters. Forty Japanese quails were equally grouped in four groups (A1 to A4) and were vaccinated by LaSota, B1, F and VG/GA strains, respectively, at the age of 10 days. Another forty Japenese quails were equally grouped in four groups (B1 to B4), were vaccinated with the vaccines of the previous groups that showed a higher effect, and were fed with mesh-feed (control-B1), supplemented with vitamin-C (B2), probiotics (B3), and antibiotic growth promoter (B4). Serum samples were obtained on 2, 4, 6, 8, 10 and 12 weeks of age and were subjected to a hemagglutination inhibition test. The mean antibody titer (Log2) had no significant difference between groups A1-A4. The highest titers were recorded in A4 (6.20±0.37) and A3 (6.00±0.71). The mean titer was significantly different among the groups at 4 weeks, but insignificant in the other weeks of the supplemented groups. A higher mean titer was found between 8 and 10 weeks in group B2 (7.40±0.60) and B3 (7.20±0.58). The relative weights (gm/kg) of the spleen, thymus and bursa were significantly higher in group B3 (1.947±0.109, 5.951±0.312 and 2.624±0.083, respectively). They had no significant correlation with antibody titer at 12 weeks. In conclusion, vitamin-C and probiotic supplemented feeds can boost up the antibody titer against ND in Japanese quail when given during VG/GA strain vaccination.

Assessment of Antibody Titer and Lymphoid Organs Weight Following Newcastle Disease Vaccination and Feed-Supplementation of Vitamin-C, Probiotics and Antibiotic-Growth-Promoters in Japanese Quails

Department of Microbiology and Public Health, Faculty of Veterinary Medicine and Animal Science

Bangabandhu Sheikh Mujibur Rahman Agricultural University

Department of Physiology, Faculty of Veterinary Science

Department of Anatomy and Histology, Faculty of Veterinary Science

Macedonian Veterinary Review

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Newcastle disease (ND) is a highly contagious viral disease. This study was conducted to determine the antibody titer in Japanese quails following vaccination...

Assessment of Antibody Titer and Lymphoid Organs Weight Following Newcastle Disease Vaccination and Feed-Supplementation of Vitamin-C, Probiotics and Antibiotic-Growth-Promoters in Japanese Quails

Published Online: Oct 26, 2021

Page range: 129 - 137

Received: Oct 22, 2020

Accepted: Feb 26, 2021

DOI: https://doi.org/10.2478/macvetrev-2021-0016

Keywords
antibody, NDV, vaccination, vitamin C, probiotics, Japanese quail

© 2021 Mirza Mienur Meher et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Assessment of Antibody Titer and Lymphoid Organs Weight Following Newcastle Disease Vaccination and Feed-Supplementation of Vitamin-C, Probiotics and Antibiotic-Growth-Promoters in Japanese Quails

Published Online: Oct 26, 2021

Page range: 129 - 137

Received: Oct 22, 2020

Accepted: Feb 26, 2021

DOI: https://doi.org/10.2478/macvetrev-2021-0016

Keywordsantibody, NDV, vaccination, vitamin C, probiotics, Japanese quail

© 2021 Mirza Mienur Meher et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
antibody, NDV, vaccination, vitamin C, probiotics, Japanese quail