<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>The aim of this study was to investigate in vitro antioxidant and antimicrobial potential of methanol and chloroform extracts of Sanguisorba minor L. subsp. muricata Briq. herba (S. minor). Total phenolic and flavonoid content of the investigated extracts were characterized. Antioxidant activity was estimated by five different in vitro assays. Antioxidant potency composite index was calculated also. Antimicrobial activity was tested against nine bacterial and one fungus strains by the micro-well dilution assay. The methanol extract of S. minor contains more phenols and shows the stronger antioxidant and antibacterial activity in comparison to the chloroform extract. However, the chloroform extract was superior to the methanol extract in content of flavonoids. Gram-positive bacteria were more sensitive than Gram-negative, to both extracts, Staphylococcus aureus being the most sensitive. Sanguisorba minor extracts were not considerably active against Candida albicans. The previous research data about Sanguisorba minor are scarce, so this data represent the first report on antimicrobial activity of S. minor. These results indicate that extracts of S. minor subsp. muricata have evidence-based potential for more comprehensive studies.</p>
</abstract>

The aim of this study was to investigate in vitro antioxidant and antimicrobial potential of methanol and chloroform extracts of Sanguisorba minor L. subsp. muricata Briq. herba (S. minor). Total phenolic and flavonoid content of the investigated extracts were characterized. Antioxidant activity was estimated by five different in vitro assays. Antioxidant potency composite index was calculated also. Antimicrobial activity was tested against nine bacterial and one fungus strains by the micro-well dilution assay. The methanol extract of S. minor contains more phenols and shows the stronger antioxidant and antibacterial activity in comparison to the chloroform extract. However, the chloroform extract was superior to the methanol extract in content of flavonoids. Gram-positive bacteria were more sensitive than Gram-negative, to both extracts, Staphylococcus aureus being the most sensitive. Sanguisorba minor extracts were not considerably active against Candida albicans. The previous research data about Sanguisorba minor are scarce, so this data represent the first report on antimicrobial activity of S. minor. These results indicate that extracts of S. minor subsp. muricata have evidence-based potential for more comprehensive studies.

Antioxidant and Antimicrobial Activity of <italic>Sanguisorba minor</italic> L. Extracts

the Faculty of Medical Sciences, Department of Pharmacy

University of Nis, the Faculty of Science and Mathematics

Experimental and Applied Biomedical Research (EABR)

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Antioxidant and Antimicrobial Activity of  L. Extracts

The aim of this study was to investigate in vitro antioxidant and antimicrobial potential of methanol and chloroform extracts of Sanguisorba minor L. subsp....

Antioxidant and Antimicrobial Activity of Sanguisorba minor L. Extracts

Published Online: Nov 26, 2019

Page range: 51 - 57

Received: Aug 29, 2019

Accepted: Sep 10, 2019

DOI: https://doi.org/10.2478/sjecr-2019-0044

Keywords
Sanguisorba minor subsp. muricata, antioxidant activity, antimicrobial activity

© 2022 Tijana Cirovic et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Antioxidant and Antimicrobial Activity of Sanguisorba minor L. Extracts

Published Online: Nov 26, 2019

Page range: 51 - 57

Received: Aug 29, 2019

Accepted: Sep 10, 2019

DOI: https://doi.org/10.2478/sjecr-2019-0044

KeywordsSanguisorba minor subsp. muricata, antioxidant activity, antimicrobial activity

© 2022 Tijana Cirovic et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
Sanguisorba minor subsp. muricata, antioxidant activity, antimicrobial activity