Comparison between two cyclooxygenase inhibitors in an experimental dry eye model in albino rabbits

A. Gulati and R. Dana, Keratoconjunctivitis sicca, Clinical aspects, in The Cornea (Eds C. S. Foster, D. T. Azar and C. H. Dohlam), 4^th ed., Lippincot, Williams and Wilkins, Philadelphia 2005, pp. 603-626.Search in Google Scholar

R. I. Fox and M. Stern, Sjogren's syndrome: Mechanisms of pathogenesis involve interaction of immune and neurosecretory systems, Scand. J. Rheumatol. 31 (2003) 3-13; DOI: 10.1080/030097402317474874.10.1080/030097402317474874Search in Google Scholar

S. C. Pflugfelder, Anti-inflammatory therapy of dry eye, Am. J. Ophthalmol. 137 (2004) 337-342; DOI: 10.1016/J.ajo.2003.10.036.10.1016/j.ajo.2003.10.03614962426Search in Google Scholar

L. Libui, D. Li, A. Doshi, W. Farely, R. M. Corrales and S. C. Pflugfelder, Experimental dry eye stimulates the production of inflammatory cytokines and MMP-9 and activates MAPK signaling pathways on the ocular surface, Invest. Ophthamol. Vis. Sci. 45 (2004) 4293-4301; DOI: 10.1167/iovs.03-1145.10.1167/iovs.03-114515557435Search in Google Scholar

A. Solomon, D. Dursun and Z. Liu, Pro and anti-inflammatory forms of interleukins in the tear fluid and conjunctiva of patients with dry eye disease, Invest. Ophthamol. Vis. Sci. 42 (2001) 2283-2292.Search in Google Scholar

T. J. Nagelhaut, D. A. Gamache, L. Roberts, M. T. Brady and J. M. Yanni, Preservation of tear film integrity and inhibition of corneal injury by dexamethasone in a rabbit model of lacrimal gland inflammation-induced dry eye, J. Ocul. Pharmacol. Ther. 21 (2005) 139-148; DOI: 10.1089/JOP.2005.21.139.10.1089/jop.2005.21.13915857280Search in Google Scholar

L. D. Waterbury, D. Silliman and T. Jalas, Comparison of cyclooxygenase inhibitory activity and ocular anti-inflammatory effects of ketorolac tromethamine and bromfenac sodium, Curr. Med. Res. Opin. 22 (2006) 1133-1140; DOI: 10.1185/03 0079906x112471.Search in Google Scholar

J. Damm, T. Rau and A. Pah, Constitutive expression and localization of COX-1 and COX-2 in rabbit iris and ciliary body, Exp. Eye Res. 72 (2001) 611-621; DOI: 10.1006/exer.2001.0977.10.1006/exer.2001.097711384149Search in Google Scholar

A. Bertolini, A. Ottani and M. Sandrini, Selective COX-2 inhibitors and dual acting anti-inflammatory drugs, critical remarks, Curr. Med. Chem. 9 (2002) 1033-1034; DOI: 10.2174/0929867-024606650.Search in Google Scholar

A. A. Steiner, S. Li, Q. J. Lianos and C. M. Blatteis, Differential inhibition by nimesulide of the early and late phases of intravenous and intracerebral neuroimmunomodulation, 9 (2001) 263-275; DOI: 10.1159/000054289.10.1159/00005428911964521Search in Google Scholar

S. Burgalassi, L. Panichi, P. Chetoni, M. F. Saettone and E. Boldrini, Development of a simple dry eye model in the albino rabbit and evaluation of some tear substituents, Ophthalmic Res. 31 (1999) 229-235; DOI: 10.1159/000055537.10.1159/00005553710224507Search in Google Scholar

X. U. Li, L. Hu, J. Hu and W. Wang, Investigation of dry eye disease and analysis of the pathogenic factors in patients after cataract surgery, Cornea 26 (2007) 516-520; DOI: 10.1097/ico.0b013e31812f67ca.10.1097/ICO.0b013e31812f67ca17881910Search in Google Scholar

L. S. Mengher, A. J. Bron, S. R. Tonge and D. J. Gilbert, Non-invasive instrument for clinical assessment of the precorneal tear film stability, Curr. Eye Res. 4 (1985) 1-7.10.3109/027136885089999603979089Search in Google Scholar

C. Tamer, I. M. Melek, T. Duman and H. Oksuiz, Tear film tests in Parkinson's disease patients, Ophthalmol. 112 (2005) 1795-1800; DOI: 10.1016/J.ophtha.2005.04.025.10.1016/j.ophtha.2005.04.02516095705Search in Google Scholar

M. D. Sternlicht and Z. Werb, How matrix metalloproteinases regulate cell behavior, Annu. Rev. Cell. Dev. Biol. 17 (2001) 463-516; DOI: 10.1146/annurev.Cellbio.17.1.463.10.1146/annurev.cellbio.17.1.463279259311687497Search in Google Scholar

D. Dursun, M. Wang, D. Monroy, D. Li, M. E. Stern and S. C. Pflugfelder, A mouse model of KCS, Invest. Ophthamol. Vis. Sci. 43 (2002) 632-638.Search in Google Scholar

P. Marsh and S. C. Pflugfelder, Topical nonpreserved methylprednisolone therapy for keratoconjunctivitis sicca in Sjogren's syndrome, Ophthalmology 106 (1999) 811-816; DOI: 10.1016/50161-6420(99)90171-9.Search in Google Scholar

R. Schalnus, Topical non steroidal anti-inflammatory therapy in ophthalmology, Ophthalmologica 217 (2003) 89-98; DOI: 10.1159/000068563.10.1159/00006856312592044Search in Google Scholar

S. E. Wilson and H. D. Perry, Long term resolution of chronic dry eye symptoms and signs after topical cyclosporine treatment, Ophthalmology 114 (2007) 76-79; DOI: 10.1016/J.ophtha.2006.05.077.10.1016/j.ophtha.2006.05.07717070588Search in Google Scholar